新生儿红斑狼疮的诊治  

Diagnosis and Treatment of Neonatal Lupus Erythematosus

作　　者：王芳[1] 张建中[1] WANG Fang;ZHANG Jianzhong(Department of Dermatology, Peking University People＇s Hospital, Beijing 100044, China)

机构地区：[1]北京大学人民医院皮肤科,北京100044

出　　处：《皮肤科学通报》2018年第3期342-345,共4页Dermatology Bulletin

摘　　要：新生儿红斑狼疮是一种少见的由母体Ro/La抗体引起的被动免疫性疾病。临床可出现婴儿暴露部位的环形红斑或斑块、先天性心脏传导阻滞,少数可见肝脏、造血系统及神经系统的累及。该病可在出生后6~8个月随母体血清抗体消失而症状逐渐消失。孕期管理、患儿皮疹外用激素、监测心脏功能等是治疗该病的关键。Neonatal lupus erythematosus is a rare immune disease caused by the passive transfer of maternal Ro/La antibody. The disease presents as annular erythema or plaques in the exposed skin and congenital heart block, visceral damage may coexist. Usually, the symptom will disappear in 6～8 months after birth with the clearance of Ro/La maternal antibody. Pregnancy management, topical steroids treatment for rash and cardiac function monitoring are the key for treatment.

关 键 词：红斑狼疮 新生儿 抗Ro/SSA抗体 抗La/SSB抗体 心脏病 

分 类 号：R593.241[医药卫生—内科学] R720.5[医药卫生—临床医学]