甲状腺全切术治疗原发性甲状腺功能亢进症疗效及对患者心脏功能和肝功能的影响  

Effect of total thyroidectomy for the treatment of primary hyperthyroidism and its effects on cardiac function and liver function of patients

作　　者：李云鹏 LI Yun-peng(The People＇s Hospital of Ningfin County, Ningjin 253400, Chin)

机构地区：[1]宁津县人民医院,253400

出　　处：《中国实用医药》2018年第19期16-17,共2页China Practical Medicine

摘　　要：目的分析甲状腺全切术(TT)对原发性甲状腺功能亢进症的治疗及对患者心脏功能、肝功能的影响。方法 78例原发性甲状腺功能亢进症患者,随机分为实验组(40例)和参照组(38例)。实验组患者采用TT治疗,参照组患者采用甲状腺次全切除术(ST)治疗。比较两组患者的手术指标、甲状腺功能亢进症复发情况以及治疗后心脏功能、肝功能指标水平。结果实验组患者术中失血量为(152.45±16.34)ml显著少于参照组的(263.67±16.78)ml,手术时间为(100.78±13.67)min显著短于参照组的(122.45±15.78)min,差异具有统计学意义(P<0.05)。治疗后,实验组患者的心脏功能指标水平均优于参照组,肝功能指标水平均低于参照组,差异具有统计学意义(P<0.05)。实验组患者甲状腺功能亢进症复发率为0显著低于参照组的26.32%,差异具有统计学意义(P<0.05)。结论 TT对原发性甲状腺功能亢进症具有显著疗效,有助于缓解患者病症、降低患者的甲状腺功能亢进症复发率,减少术中失血量,缩短手术时间,对心脏功能、肝功能具有改善作用。Objective To analyze the effect of total thyroidectomy （TT） for the treatment of primary hyperthyroidism and its effects on cardiac function and liver function of patients. Methods 78 patients with primary hyperthyroidism were randomly divided into the experimental group for 40 cases and the reference group for 38 cases. The experimental group was treated with total thyroidectomy, the reference group was treated with subtotal thyroidectomy （ST）. The operative indexes, recurrence of hyperthyroidism the levels of cardiac function and liver function after treatment between the two groups were compared. Results The intraoperative blood loss of experimental group was （152.45 ± 16.34） ml, which wsa significantly less than （263.67 ± 16.78） ml of reference group, the operative time of experimental group was （100.78± 13.67） min, which wsa significantly shorter than （122.45 ± 15.78） min of reference group, the differences were statistically significant （P〈0.05）. After treatment, the levels of cardiac function indexes in experimental group were significanly better than those in reference group, the levels of liver function indexes in experimental group were significanly lower than those in reference group, the differences were statistically significant （P〈0.05）. The recurrence rate of hyperthyroidism in the experimental group was 0, which was significantly lower than 26.32% in the reference group, the difference was statistically significant （P〈0.05）. Conclusion Total thyroidectomy for the treatment of primary hyperthyroidism has obvious curative effect, helps to relieve symptoms of patients, reduce the recurrence rate of hyperthyroidism patients, reduce the intraoperative blood loss, shorten the operative time, has beneficial effects on cardiac function and liver function.

关 键 词：甲状腺全切术 原发性甲状腺功能亢进症 心脏功能 肝功能 

分 类 号：R653[医药卫生—外科学]