围产期母儿肠道微生物定植的影响因素  

Factors affecting colonization of maternal and fetal gut microbiota during perinatal period

作　　者：王赛兰 吴丹[1] 杨娜娜[1] 孙丽洲[1] Wang Sailan;Wu Dan;Yang Nana;Sun Lizhou(Department of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China)

机构地区：[1]南京医科大学第一附属医院妇产科,210029

出　　处：《中华围产医学杂志》2018年第7期495-498,共4页Chinese Journal of Perinatal Medicine

摘　　要：肠道微生物种类高达人体基因库的10倍多，约有10“个微生物定植在肠道中，被广泛认为是“第二基因库”。目前已有研究表明，“母体肠道菌群-胎盘微生物-胎儿肠道微生物”对新生儿肠道微生物神经机制、免疫调节、代谢组学等发挥了重要作用，肠道微生物组学的研究得到了广泛的推进。本文对围产期母体、母体-胎儿、新生儿肠道微生物定植的影响因素进行了综述。Human gut microbiota contains around 10TM colonized intestinal microbes. Gut microbiome outnumbers the human gene pool by ten to one. Therefore, it＇s generally considered to be our ＂second gene pool＂. Several research have clarified that the cycle of ＂maternal intestinal microbes-placental microbes-fetal intestinal microbes＂ plays a critical role in the neurological and immune regulation and metabolism in infants, which may contribute to the furtherance of research on gut microbes. We summarized the factors affecting the colonization of maternal and fetal gut microorganisms during perinatal period from recent research.

关 键 词：围产期 胃肠道微生物组 

分 类 号：R714.7[医药卫生—妇产科学]