血培养联合血清PCT和hs-CRP检测在诊断新生儿败血症中的应用分析  

Application analysis of detection of blood culture combined with serum procalcitonin and hypersensitive C-reactive protein in the diagnosis of neonatal septicemia

作　　者：孙溯荫[1] SUN Su-yin.(Guangdong Xinyi People＇ s Hospital, Xinyi 525300, Chin)

机构地区：[1]广东省信宜市人民医院,525300

出　　处：《中国实用医药》2018年第18期28-29,共2页China Practical Medicine

摘　　要：目的观察在新生儿败血症的诊断中采取血培养联合血清降钙素原(PCT)和超敏C反应蛋白(hs-CRP)检测分析。方法选择12例败血症患儿作为A组,12例局部感染者患儿为B组,12例健康新生儿作为C组。比较三组新生儿血培养、PCT、hs-CRP、联合检测阳性情况,以及全身感染相关器官功能衰竭评分法(SOFA)评分。结果 A组新生儿血培养、PCT、hs-CRP、联合检测阳性率均高于B组和C组,B组新生儿血培养、PCT、hs-CRP、联合检测阳性率均高于C组,差异具有统计学意义(P<0.05);A组新生儿SOFA评分(9.32±1.07)分高于B组的(4.32±0.54)分和C组的(0.88±0.02)分,B组新生儿SOFA评分高于C组,差异具有统计学意义(P<0.05)。结论在新生儿败血症筛查中,选取血培养联合PCT、hs-CRP检测,可提高新生儿败血症的诊断准确率,可用于新生儿败血症新型诊断标准。Objective To observe the application analysis of detection of blood culture combined with serum procalcitonin（PCT） and hypersensitive C-reactive protein（hs-CRP） in the diagnosis of neonatal septicemia.Methods 12 neonates were selected in our hospital as group A, 12 neonates with local infection were selected as group B, and 12 cases of healthy were selected as group C. The positive rates of blood culture, PCT, hs-CRP and joint detection, the score of systemic infection related organ failure（SOFA） in three groups were compared. Results The positive rates of blood culture, PCT, hs-CRP and joint detection in group A were significantly higher than those of group B and group C, and those of group B were significantly higher than group C, the differences were statistically significant（P〈0.05）. The SOFA scores of group A, group B, group C were（9.32±1.07）,（4.32±0.54） and（0.88±0.02） scores, among them, the group A was significantly higher than group B and group C, the group B was significantly higher than group C, the differences were statistically significant（P〈0.05）. Conclusion In neonatal septicemia screening, blood culture combined with PCT and hs-CRP detection can improve the diagnostic accuracy of neonatal septicemia, and it can be used for new diagnostic criteria of neonatal septicemia.

关 键 词：血培养 血清降钙素原 超敏C反应蛋白 新生儿败血症 应用分析 

分 类 号：R722.131[医药卫生—儿科]