胰十二指肠切除术后胰瘘发生的危险因素及风险预测  

Risk factors and risk prediction of pancreatic fistula after pancreaticoduodenectomy

作　　者：吴耐 张蓬波 任泽强 WU Nai;ZHANG Pengbo;REN Zeqiang(Department of Pancreatic Surgery,Affiliated Hospital of Xuzhou Medical University,Xuzhou,]iangsu 221000,P.R.China)

机构地区：[1]徐州医科大学附属医院胰腺外科,江苏徐州221000

出　　处：《中国普外基础与临床杂志》2018年第7期889-894,共6页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结胰十二指肠切除术后胰瘘发生的危险因素并探讨胰瘘风险预测系统的临床应用。方法复习近年来国内外有关胰十二指肠切除术后胰瘘危险因素及风险预测系统研究的相关文献并进行综述。结果胰十二指肠切除术后胰瘘发生的危险因素众多,包括患者自身因素(性别、年龄、基础疾病等)、疾病相关因素(胰腺质地、胰管直径、病理类型等)及手术相关因素(手术时间、术中失血量、吻合方式、胰管引流等)。胰瘘风险预测系统对胰十二指肠切除术后胰瘘发生的预测具有较好的准确度。结论胰十二指肠切除术后胰瘘发生最重要的危险因素为胰腺质地软、胰管直径小;胰瘘风险预测系统的临床应用价值大,有助于术后胰瘘的预防。Objective To summarize risk factors of pancreatic fistula after pancreaticoduodenectomy and to investigate clinical application of pancreatic fistula risk prediction system. Method The literatures of the risk factors and risk prediction of pancreatic fistula after the pancreaticoduodenectomy were collected to make a review. Results There were many risk factors for pancreatic fistula after pancreatoduodenectomy, including the patient＇s own factors （gender, age, underlying diseases, etc.）, disease related factors （pancreatic texture, diameter of pancreatic duct, pathological type, etc.）, and surgical related factors （operation time, intraoperative blood loss, anastomosis, pancreatic duct drainage, etc.）. The fistula risk prediction system after the pancreatoduodenectomy had a better forecast accuracy. Conclusions Occurrence of pancreatic fistula after pancreaticoduodenectomy is related to softness of pancreas and small diameter of pancreatic duct. Pancreatic fistula risk prediction system is helpful for prevention of pancreatic fistula after pancreaticoduodenectomy.

关 键 词：胰十二指肠切除 胰瘘 危险因素 风险预测 

分 类 号：R656[医药卫生—外科学]