负载型联三吡啶钯催化剂的制备及在Suzuki-Miyaura偶联反应中的应用  

Preparation of Supported Terpyridine-palladium Based Catalyst and Application on the Suzuki-Miyaura Coupling Reaction

作　　者：黄一波[1] 陈绘如[1] 张文雯[1] HUANG Yi-bo;CHEN Hui-ru;ZHANG Wen-wen(Jiangsu Provincial Applied Enzyme Engineering Technology and Develop- ment Center, School of Pharmaceutical and Environmental Engineering, Changzhou Vocational Institute of Engineering, Changzhou 213164, China)

机构地区：[1]常州工程职业技术学院制药与环境工程学院江苏省应用酶工程技术开发中心

出　　处：《化学试剂》2018年第7期683-686,694,共5页Chemical Reagents

基　　金：常州工程职业技术学院“绿色催化与应用酶”院级科研团队资助项目(2017);江苏省教育厅高校自然科学基金面上项目(17KJD150001)

摘　　要：以4-（对羟基苯基）-2,2＇;6＇,2″-联三吡啶为配体,盐酸活化的硅胶为载体,制备了二氧化硅负载的钯催化剂Si O2-tpy-Pd。120℃下,DMF为溶剂、K2CO3作为碱,四丁基溴化铵（TBAB）为相转移催化剂,负载型Si O2-tpy-Pd催化剂用量为0.5 mol%,可有效促进芳基卤与芳硼酸的Suzuki-Miyaura偶联反应。该负载钯催化剂循环使用6次,催化活性无显著降低。The SiO2 supported terpyridine-palladium（ SiO2-tpy-Pd） catalyst was prepared by 4-（ [2,2＇; 6＇,2″-terpyridin]-4＇-yl）phenol as ligand and silica gel as carrier.The Suzuki-Miyaura reaction of aryl halide with aryl boric acid can be effectively promoted under the reaction temperature of 120 ℃,DMF as solvent,K2CO3 as base,TBAB as phase transfer catalyst,supported catalyst loading 0. 5 mol%.The catalyst can be reused at least six times without distinct activity decrease.

关 键 词：联三吡啶 钯催化剂 偶联反应 

分 类 号：O62[理学—有机化学] O69[理学—化学]