平阳霉素治疗咽喉部血管瘤  

Treatment of pharyngeal and laryngeal hemangiomas with pingyangmycin

作　　者：许雯[1] 汤玮[1] 余少卿[1] 李少辉[1] 葛荣明[1] XU Wen;TANG Wei;YU Shaoqing;LI Shaohui;GE Rongming(Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji University, Shanghai 200065, Chin)

机构地区：[1]同济大学附属同济医院耳鼻咽喉头颈外科,上海200065

出　　处：《山东大学耳鼻喉眼学报》2018年第4期62-64,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的探讨支撑喉镜下平阳霉素局部注射治疗咽喉部血管瘤的疗效。方法 16例咽喉部血管瘤患者经支撑喉镜下行瘤体内多次、多点注射平阳霉素。结果 16例患者中,治愈14例(87.50%),有效2例(12.50%)。2例出现低热,1例出现轻度胃肠道反应,其余病例无并发症发生。平阳霉素局部注射1次3例,2次9例,3次3例,4次1例。随访6个月以上,均未见血管瘤复发。结论平阳霉素治疗咽喉部血管瘤效果明显,创伤小,值得推广。Objective To investigate the therapeutic effect of local injection of pingyangmycin using suspension laryngoscopy for treatment of pharyngeal and laryngeal hemangiomas.Methods Sixteen patients with pharyngeal and laryngeal hemangiomas received multiple injections of pingyangmycin at various locations in the hemangiomas under the guidance of a suspension laryngoscope.Results A total of 16 patients received local injections of pingyangmycin.Among them,the cancer was completely cured in 14（87.50%） patients,while the remaining 2（12.50%）.With respect to complications,2 patients developed low-grade fever and 1 had a mild gastrointestinal reaction.Three of the patients received a single injection of pingyangmycin,9 received it twice,3 received it thrice,and 1 received it 4 times.None of them had a relapse over the 6-month follow-up period.Conclusion Pingyangmycin is effective for the treatment of pharyngeal and laryngeal hemangiomas,though there is some risk of adverse events.

关 键 词：平阳霉素 支撑喉镜 血管瘤 咽喉部 

分 类 号：R766.5[医药卫生—耳鼻咽喉科]