Expedient chemoselective and catalyst-free synthesis of 3,3-difluorochroman-4-ones from o-hydroxyarylenaminones and Selectfluor  

作　　者：Jian Xu Zhijie Kuang Qiuling Song 

机构地区：[1]Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University

出　　处：《Chinese Chemical Letters》2018年第6期963-966,共4页中国化学快报（英文版）

基　　金：Financial support from the Recruitment Program of Global Experts (1000 Talents Plan);the Natural Science Foundation of Fujian Province (No. 2016J01064);Fujian Hundred Talents Plan, Program of Innovative Research Team of Huaqiao University (No. Z14X0047);Subsidized Project for Cultivating Postgraduates’ Innovative Ability in Scientific Research of Huaqiao University (for Z. Kuang) are gratefully acknowledged

摘　　要：An expedient and mild strategy for the synthesis of unconventional 2-（dimethylamino）-3,3-difluorochroman-4-one derivatives from o-hydroxyarylenaminones and Selectfluor was developed at room temperature under catalyst-free conditions. This method showed excellent chemoselectivity and great functional groups tolerance.An expedient and mild strategy for the synthesis of unconventional 2-（dimethylamino）-3,3-difluorochroman-4-one derivatives from o-hydroxyarylenaminones and Selectfluor was developed at room temperature under catalyst-free conditions. This method showed excellent chemoselectivity and great functional groups tolerance.

关 键 词：SELECTFLUOR o-Hydroxyarylenaminones CATALYST-FREE Chroman-4-one Fluorination reaction Fluorine-contained compound 

分 类 号：O621.3[理学—有机化学]