侧链悬挂辣素衍生结构丙烯酸树脂的合成及抗菌性能研究  

Synthesis and antibacterial activity of acrylate resin with capsaicin in the side chain

作　　者：赵海洲[1] 倪春花[1] 于良民[1] 李霞[1] ZHAO Haizhou;NI Chunhua;YU Liangmin;LI Xia(Key Laboratory of Marine Chemistry Theory and Technology,Ministry Ocean University of China,Qingdao 266100,China)

机构地区：[1]中国海洋大学海洋化学理论与工程技术教育部重点实验室,山东青岛266100

出　　处：《功能材料》2018年第7期7134-7137,7143,共5页Journal of Functional Materials

基　　金：国家自然科学基金资助项目(41576077)

摘　　要：以实验室自主合成的辣素类化合物——N-(4-羟基-2-甲基-5-甲硫基苄基)丙烯酰胺(HMMBA)为功能单体,通过与丙烯酸酯类单体的自由基聚合反应,合成出侧链悬挂辣素衍生结构的丙烯酸树脂,采用红外光谱(IR)和核磁氢谱(1 H NMR)对其结构进行了表征。考察了引发剂用量、聚合温度、聚合时间对树脂合成的影响,并确定了树脂的最佳合成条件为,引发剂用量为单体质量的1.5%,聚合温度为100℃,聚合时间为8h。以自然界常见细菌大肠杆菌作为受试菌对所合成的树脂进行了抗菌性能测试,实验结果表明,随着HMMBA含量的增加,树脂的抗菌率也相应增大。The acrylate resin with capsaicin in the side chain was synthesized with self-made compound 4-hydroxy-2-methyl-5-methylthio benzyl acrylamide（HMMBA）and acrylate monomer by radical polymerization,and the structure was characterized by infrared spectroscopy（IR）and hydrogen nuclear magnetic spectra（1 H NMR）.The effects of the amount of initiator,polymerization temperature and polymerization time on the resin synthesis were investigated and the optimal synthesis conditions of the resin were determined as follows.The amount of initiator was 1.5% of monomer mass,the polymerization temperature was 100 ℃ and the polymerization time was 8 h.The antibacterial activity of the synthesized resin was tested by using the common bacteria Escherichia coli in the nature as the tested bacteria.The experimental results showed that the antibacterial rate of the prepared resin to Escherichia coli increased with the increase of HMMBA content.

关 键 词：辣素 丙烯酸树脂 合成 抗菌性 防污 

分 类 号：TQ637.2[化学工程—精细化工]