惠州地区B群链球菌感染与不良妊娠结局的相关性分析  

Analysis of The Correlation Between Group B Streptococcus Infection on The Pregnant Women and The Adverse Pregnancy Outcome of Huizhou

作　　者：欧阳惠君 廖奔兵 靖吉芳 林保安 李康生[1] OU-YANG Huijun;LIAO Benbing;JING Jifang;LIN Bao＇an;LI Kangsheng(Department of Microbiology and lmmunology, Shantou University Medical College, Shantou 515041, China;Huizhou Health Sciences Polytechnic, Huizhou 516025, China;Women-Children Care and Family Planning Service Center ofHuizhou, Huizhou 516025, China.)

机构地区：[1]汕头大学医学院微生物学与免疫学教研室,广东汕头515041 [2]惠州卫生职业技术学院,广东惠州516025 [3]惠州市妇幼保健计划生育服务中心,广东惠州516025

出　　处：《汕头大学医学院学报》2018年第2期93-94,98,共3页Journal of Shantou University Medical College

基　　金：惠州市科技计划项目(2017Y091)

摘　　要：目的:分析惠州地区妊娠晚期妇女B群链球菌(GBS)感染与不良妊娠结局的相关性。方法:将426例孕35~42周妇女按是否感染B群链球菌分为观察组(GBS阳性组)和对照组(GBS阴性组)。回顾性分析其胎膜早破、早产、宫内感染、胎儿宫内窘迫、胎儿生长受限等不良妊娠结局的发生频次,并进行统计分析。结果:妊娠中晚期妇女GBS阳性组胎膜早破的发生率为62.44%,GBS阴性组胎膜早破的发生率为52.11%,GBS阳性组胎膜早破发生率比阴性组高10.33%,差异具有统计学意义(P<0.05)。其他不良妊娠结局均与GBS是否感染不相关。结论:B群链球菌感染是胎膜早破发生的独立危险因素。对GBS感染的孕妇,应尽早进行临床干预。Objective： To analysis the correlation between group B streptococcus infection on the pregnant women in late gestation and the adverse pregnancy outcome of Huizhou. Methods：426 women of 35 to 42 weeks of gestation were divided into the observation group（GBS positive group） and the control group（GBS negative group） according to whether they were infected with group B streptococcus. Making a retrospective analysis of the frequency of adverse pregnancy outcomes such as premature rupture of membranes, premature delivery, intrauterine infection, fetal distress, fetal growth retardation. Results： The incidence of premature rupture of membranes was 62% in GBS-positive women and 52% in GBS-negative women during the third trimester of pregnancy. The rate of premature rupture of membranes in the GBS-positive group was 10% higher than that in the negative group and it is statistically significant（P〈0.05）. Other adverse pregnancy outcomes were not associated with GBS infection. Conclusion： Group B streptococcal infection is an independent risk factor for premature rupture of membranes. Clinical intervention on the GBS-infected women of gestation should be conducted as soon as possible.

关 键 词：B群链球菌 GBS 胎膜早破 不良妊娠结局 

分 类 号：R446.5[医药卫生—诊断学]