艾灸对持续植物状态患者骨代谢的影响  

The influence of moxibustion on the bone metabolism of persistent vegetative state patients

作　　者：张绍华 王玉龙[2] 肖鹏 曾小利 Zhang Shaohua;Wang Yulong;Xiao Peng;Zeng Xiaoli(The Rehabilitation Department of Shenzhen Nan ＇ao People＇s Hospital,Shenzhen 518121,China)

机构地区：[1]广东省深圳市大鹏新区南澳人民医院康复科,518121 [2]广东省深圳市第二人民医院康复科,518035

出　　处：《国际中医中药杂志》2018年第7期596-599,共4页International Journal of Traditional Chinese Medicine

基　　金：深圳市大鹏新区产业发展项目（YL2016305）

摘　　要：目的 观察艾灸对持续性植物状态（persistent vegetative state, PVS）患者骨代谢的影响。方法 将符合入选标准的60例PVS患者采用随机数字表法分为2组，每组30例。2组患者均给予西医常规治疗及护理，在此基础上对照组口服碳酸钙D3片，治疗组联合艾灸中脘、下脘、气海、关元穴。2组均治疗12周。采用双能X线骨密度仪测量桡骨远端、第2腰椎和股骨上端的骨密度（bone mineral density, BMD），采用琼脂糖凝胶电泳测量血清ALP水平，采用放射免疫法测定降钙素（calcitonin, CT）、骨钙素（bone gla-protein, BGP）水平，采用电化学发光免疫法测定血钙（Ca）、磷（P）、甲状旁腺素（parathyroid hormone, PTH）浓度。结果 治疗后，治疗组桡骨远端[（0.563±0.205）g/cm2比（0.451±0.114）g/cm2，t＝2.615]，第二腰椎[（0.596±0.108）g/cm2比（0.533±0.127）g/cm2，t＝2.069]，股骨颈[（0.567±0.214）g/cm2比（0.463±0.163）g/cm2，t＝2.117]骨密度均高于对照组（P＜0.05）；血清PTH[（6.41±0.56）pmol/L比（6.72±0.42）pmol/L，t＝0.018]、CT[（217.48±57.35）ng/L比（228.46±52.44）ng/L，t＝0.012]、BGP[（9.16±1.57）g/L比（10.37±2.37）g/L，t=0.023]水平均低于对照组（P＜0.05）。结论 艾灸可明显改善PVS患者的骨代谢，防治骨质疏松。Objective To observe the influence of moxibustion on the bone metabolism of persistent vegetative state patients. Methods A total of 60 patients with persistent vegetative state were divided randomly into the treatment group and control group, 30 in each. Both groups were treated with routine therapy, and the patients used moxibustion on the acupoints of zhongwan, xiawan, qihai and guanyuan. The treatment lasted 12 weeks. The changes of T-lymphoctyte subgroups, serum immunoglobulin were tested and compared before and 12th week after treatment. Result After 12th week treatment, the BMD of distal radius （0.563 ± 0.205 g/cm2 vs. 0.451 ± 0.114 g/cm2, t=2.615）, the second lumbar vertebra （0.596 ± 0.108 g/cm2 vs. 0.533 ± 0.127 g/cm2, t=2.069） and the femoral neck （0.567 ± 0.214g/cm2 to 0.463 ± 0.163g/cm2, t=2.117） in the treatment group were significantly higher than those in the control group （Ps〈0.05）. The PTH （6.41 ± 0.56 pmol/L vs. 6.72 ± 0.42 pmol/L, t=0.018）, CT （217.48 ± 57.35 ng/L vs. 228.46 ± 52.44ng/L, t=0.012） and BGP （9.16 ± 1.57 g/L vs. 10.37 ± 2.37 g/L, t=0.023） in the treatment group were significantly higher than those in the control group （Ps〈0.05）. Conclusions Moxibustion can help to treat the bone metabolism of persistent vegetative state patients and prevent the osteoporosis.

关 键 词：艾条灸 持续植物人状态 骨代谢 骨密度 骨质疏松 

分 类 号：R246.6[医药卫生—针灸推拿学]