卡前列素氨丁三醇应用于高危妊娠产后出血的临床效果分析  

Analysis of Clinical Effect of Romethamine in the Postpartum Hemorrhage of High-risk Pregnancy

作　　者：常红艳[1] CHANG Hong-yan(Department of Gynecology and Obstetrics,Hospital of Zibo Mining Group Co,Ltd,Zibo,Shandong Province,255120 China)

机构地区：[1]淄博矿业集团有限责任公司中心医院妇产科,山东淄博255120

出　　处：《中外医疗》2018年第10期124-126,共3页China & Foreign Medical Treatment

摘　　要：目的对卡前列素氨丁三醇防治高危妊娠产后出血的疗效进行分析探讨。方法方便选取2015年1月—2017年8月该院收治的110例高危妊娠患者,随机分为两组,对照组55例患者在胎儿娩出之后采用缩宫素治疗,观察组55例患者在胎儿娩出之后采用缩宫素联合卡前列素氨丁三醇注射液治疗,对比两组患者产后出血发生率、凝血指标及不良反应发生率。结果观察组分娩72 h后的APTT、RT、BPC及Fg指标分别为(35.64±4.92)s、(16.62±2.54)s、(165.46±17.91)×109/L、(4.71±0.67)g/L,明显优于对照组的(30.37±2.66)s、(14.03±2.79)s、(186.15±18.29)×109/L、(4.22±0.49)g/L(t=5.245、4.223、8.907、5.116,P<0.05)。观察组患者术后2 h及24 h的出血量为(125.16±19.07)、(220.94±22.42)m L,明显少于对照组的(239.64±21.63)、(390.41±24.73)m L(t=6.251、5.407,P<0.05),术后24 h尿量为(1 522.52±188.46)m L,明显多于对照组的(1 028.66±194.27)m L(t=11.922,P<0.05)。结论对高危妊娠产妇产后采用卡前列素氨丁三醇治疗能够有效提高治疗效果,降低产后出血发生率及不良反应发生率,值得临床应用推广。Objective To study and analyze the clinical effect of romethamine in the postpartum hemorrhage of high-risk pregnancy. Methods 110 cases of high-risk pregnancy patients admitted and treated in our hospital from January 2015 to August 2017 were convenient selected and randomly divided into two groups with 55 cases in each, the control group were treated with oxytocin, while the observation group were treated with romethamine and oxytocin, and the incidence rate of postpartum hemorrhage, coagulation indicators and incidence rate of adverse reactions were compared between the two groups. Results The APTT, RT, BPC, Fg in the observation group after 72 h delivery were obviously better than those in the control group,[（35.64±4.92）s,（16.62±2.54）s,（165.46±17.91）×10^9/L,（4.71±0.67）g/L vs（30.37±2.66）s,（14.03±2.79）s,（186.15±18.29）×109^/L,（4.22±0.49）g/L]（t=5.245,4.223,8.907,5.116,P〈0.05）, and the bleeding amounts in 2 h and 24 h after surgery in the observation group were obviously lower than those in the control group, [（125.16±19.07）mL,（220.94±22.42）mL vs（239.64±21.63）mL,（390.41±24.732）mL]（t=6.251,5.407,P〈0.05）, and the urinary volume in 24 h after surgery was obviously more than that in the control group, [（1 522.52±188.46）mL vs（1 028.66±194.27）mL]（t=11.922,P〈0.05）. Conclusion The romethamine in the postpartum hemorrhage of high-risk pregnancy in high-risk gestational delivery women can effectively improve the treatment effect, reduce the incidence rate of postpartum hemorrhage and incidence rate of adverse reactions, and it is worth clinical promotion and application.

关 键 词：卡前列素氨丁三醇 高危妊娠 产后出血 

分 类 号：R714[医药卫生—妇产科学]