外周血淋巴细胞/中性细胞百分比在急性复杂性阑尾炎诊断中的价值  被引量:4

The value of peripheral blood lymphocyte - neutrophil ratio in the diagnosis of complicated acute appendicitis

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作  者:孙玉佳 刘斯[1] 高雨松[1] 汪波[1] 熊辉[1] Sun Yu-jia;Liu Si;Gao Yu-song;Wang Bo;Xiong Hui(Department of Emergency,Peking University First Hospital,Beijing 100034,China)

机构地区:[1]北京大学第一医院急诊科,北京100034

出  处:《中国急救医学》2018年第7期608-611,共4页Chinese Journal of Critical Care Medicine

摘  要:目的 讨论在血常规中是否存在某些炎性指标可以评估急性阑尾炎的严重程度,进而为急性阑尾炎的保守治疗提供指导。方法 回顾分析北京大学第一医院179例急性阑尾炎患者行阑尾切除术的临床资料。依据手术病理结果,分为急性非复杂性阑尾炎(uncomplicated acute appendicitis,UAA)组和急性复杂性阑尾炎(complicated acute appendicitis,CAA)组,并对两组间的首诊外周血血常规结果进行统计学分析。结果 179例急性阑尾炎患者,其中85例(47.49%)为UAA,94例(52.51%)为CAA,通过统计学方法比较,发现CAA患者比UAA患者的淋巴细胞计数(the lymphocyte count,LY)、淋巴细胞百分比(the lymphocytes percent,LY%)和淋巴细胞/中性粒细胞百分比(the lymphocyte-neutrophil ratio,LNR%)下降更为明显,LY平均值为(1.53±1.03)×10^9 /L(UAA组)和(1.10±0.65)×10^9 /L(CAA组),P=0.001;LY%平均值为(12.56±7.72)%(UAA组)和(7.80±4.87)%(CAA组),P=0.000;LNR%平均值为(17.69±15.95)%(UAA组)和(9.45±7.43)%(CAA组),P=0.000。结论 外周血LY、LY%和LNR%可以评估急性阑尾炎的严重程度。Objective This study aims at identifying the relationship between the routine blood test features and the severity of acute appendicitis to provide guidance for conservative treatment. Methods A retrospective clinical analysis was made on 179 appendectomy patients with acute appendicitis in Peking University First Hospital. According to pathology reports of all cases, the initial preoperative blood routine examination results were statistically evaluated at different stages of acute appendicitis (uncomplicated acute appendicitis vs. complicated acute appendicitis ). Results 179 patients of acute appendicitis included 85 patients (47.49%) with uncomplicated acute appendicitis (UAA) and 94 patients (52.51%) with complicated acute appendicitis (CAA). Statistical analysis indicates that patients with CAA have significant decreases compared with UAA in the lymphocyte count (LY) [ ( 1.53 ± 1.03 ) ×10^9/L vs. ( 1. 10± 0.65) ×10^9/L, P = 0. 001 ] and lower rates of the lymphocyte percentage ( LY% ) [ ( 12.56 ± 7.72) % vs. (7.80 ± 4.87 ) %, P = 0.000 ] and lymphocyte - neutrophil ratio(LNR% ) [ (17.69±15.95)% vs. (9.45 ±7.43)%, P=0.000]. Conclusion LY, LY% and LNR% can be useful to evaluate the severity of acute appendicitis.

关 键 词:急性阑尾炎 保守治疗 淋巴细胞 

分 类 号:R593.241[医药卫生—内科学]

 

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