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作 者:黄超洋[1] 张恒娇[1] 高立冬[1] 黄一伟[1] 邓志红[1] 李芳彩[1] 李文超[1] 刘运芝[1] 湛志飞[1] 李俊华[1] 张红[1] HUANG Chao-yang;ZHANG Heng-jiao;GAO Li-dong;HUANG Yi-wei;DENG Zhi-hong;LI Fang-cai;LI Wen-chao;LIU Yun-zhi;ZHAN Zhi-fei;LI Jun-hua;ZHANG Hong(Hunan Provincial Center for Disease Control and Prevention,Changsha,Hunan 410005,China)
机构地区:[1]湖南省疾病预防控制中心,湖南长沙410005
出 处:《实用预防医学》2018年第8期897-901,共5页Practical Preventive Medicine
基 金:国家重大专项(2013ZX10004202-001-003);湖南省科技厅资助项目(2014SK3246);湖南省卫生厅重点课题(A2011-006)
摘 要:目的了解2007-2016年湖南省流感流行规律,为今后的流感防控工作提供科学依据。方法运用描述流行病学方法对2007-2016年湖南省流感样病例(influenza like illness,ILI)数据、流感毒株分离数据和流感暴发疫情数据进行分析。结果 2007-2016年哨点医院共报告ILI病例1 520 652例,占就诊病人总数的百分比(ILI%)为4.82%。0~岁、5~岁、15~岁、25~岁和60~岁五个年龄组的ILI人数分别占ILI病例总数的65.98%、20.77%、4.49%、6.68%和2.08%;湖南省流感流行呈现冬春季和夏季双高峰;共分离到流感病毒8 788株,分离率为5.99%,毒株分型为H1N1 476株、新甲型(H1N1)pdm09(新甲H1)2 422株、H3N2 2 985株、B型Yamagata系(BY)1 361株和Victorian系(BV)1 532株、未定型12株,不同型别毒株每隔1~2年成为优势毒株;共报告ILI暴发疫情264起,230起发生在中、小学校,占总疫情的87.12%。结论冬春季和夏季是湖南省的流感流行高峰;H3、新甲型H1和B型流感毒株每隔1~2年交替成为优势毒株;中小学校是流感暴发疫情的高发场所,应重点加强防控。Objectvie To investigate the regularity of influenza epidemics in Hunan Province during 2007-2016,and to provide a scientific basis for prevention and control of influenza in future. Methods Descriptive epidemiological methods were used to analyze the data concerning influenza like illness( ILI) cases,types/subtyps of influenza virus strains and influenza outbreaks reported in Hunan Province during 2007-2016. Results A total of 1,520,652 ILI cases were reported by sentinel hospitals during 2007-2016,accounting for 4.82% of the total outpatients from all the sentinel clinics. The number of ILI patients in the age groups of 0-,5-,15-,25-and 60-years respectively accounted for 65.98%,20.77%,4.49%,6.68% and 2. 08% of the total ILI cases. Influenza epidemics peaked annually during the winter-spring and summer months in Hunan Province. A total of8,788( 5.99%) influenza virus strains were isolated,including 476 strains of seasonal A( H1 N1),2,422 strains of A( H1 N1)pdm09,2,985 strains of H3 N2,1,361 strains of subtype B of Yamagata( BY),1,532 strains of subtype B of Victorian( BV) and12 strains of unknown type. The predominant strain changed every 1-2 years,and appeared alternately. A total of 264 ILI outbreaks were reported,and 230 occurred in primary and secondary schools,accounting for 87.12% of the total outbreaks. Conclusions There are two peaks of influenza epidemic each year in Hunan Province,one in winter-spring and a second in summer.H3,A( H1 N1) pdm09 and type B strains are alternately dominant in an interval of 1-2 years. Prevention and control of influenza outbreaks should be focused on primary and secondary schools.
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