武汉地区959例甲真菌病临床及致病菌菌种分析  

Clinical Investigation of 959 Cases of Onychomycosis and Analysis of the Pathogenic Fungus in Wuhan Area

作　　者：董婧[1] 杨静[1] Dong Jing;Yang Jing(Department of Dermatology,First Hospital of Wuhan,Wuhan 430022,Chin)

机构地区：[1]武汉市第一医院皮肤科,武汉430022

出　　处：《华中科技大学学报（医学版）》2018年第4期470-472,共3页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：湖北省自然科学基金资助项目(No.2011CDB303)

摘　　要：目的了解武汉地区2017年甲真菌病患者的临床特征,致病真菌菌种构成及其分布。方法收集2017年1月~12月期间来武汉市第一医院皮肤科门诊就诊行真菌培养患者临床资料及培养结果进行统计分析。结果 1561例甲真菌培养患者,真菌培养阳性959例,阳性率61.4%。致病菌中皮肤癣菌占85.51%,酵母菌占9.59%,非皮肤癣菌占4.90%。皮肤癣菌中,红色毛癣菌占80.29%,须癣毛癣菌占2.92%,紫色毛癣菌占1.46%。酵母菌中主要为念珠菌占6.46%,其他非皮肤癣菌以曲霉菌为主,占2.50%。结论武汉地区甲真菌病致病菌种以皮肤癣菌为主,最主要的为红色毛癣菌,紫色毛癣菌所占比例上升。Objective To investigate the main clinical features,the causative pathogens and the epidemiology of pathogenic fungi of onychomycosis in Wuhan.Methods A total of 1561 outpatients were enrolled from Jan.2017 to Dem.2017.Fungal culture and clinical analysis were performed on 1561 cases of onychomycosis by using microscopic examination.Results Totally,959 strains were isolated,and the positive rate was 61.4%.The positive rate of dermatophytes,yeasts and non-dermatophytic moulds were 85.51%,9.59% and 4.90%,respectively.Trichophyton rubrum accounted for 80.29% of dermatophytes,trichophyton entagrophytes 2.92% and trichophyton purplera 1.46%.The yeasts mainly included candida（6.46%）.Non-dermatophytie moulds mainly included aspergillus（2.5%）.Conclusion The analysis shows that the major pathogenic fungi of onychomycosis is dermatophytes,the main dermatophyte is T.rubrum,and the proportion of T.purplerais increasing in Wuhan.

关 键 词：甲真菌病 武汉地区 致病真菌 流行病学 

分 类 号：R756.4[医药卫生—皮肤病学与性病学]