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作 者:朱怡恬 陈颖 项兰兰 汪晓曼 孙慧谨[1] ZHU Yitian;CHEN Ying;XIANG Lanlan;WANG Xiaoman;SUN Huijin(Clinical Laboratory,Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University,Nanjing Jiangsu 210004,China;Clinical Laboratory,Jiangsu Provincial People's Hospital,Nanjing Jiangsu 210029,China)
机构地区:[1]南京医科大学附属妇产医院检验科,江苏南京210004 [2]江苏省人民医院检验科,江苏南京210029
出 处:《中国继续医学教育》2018年第22期51-53,共3页China Continuing Medical Education
摘 要:目的调查和分析本地区双胞胎婴幼儿的微量元素水平的变化。方法收集2016年1月—2017年6月至本院健康体检的双胞胎婴幼儿371对作为研究组。随机收集2016年1月—2017年6月2 123例非多胞胎婴幼儿作为对照组。根据年龄不同,将研究组和对照组分别分为5组:5~6个月(m)、7~11个月(m)、12个月(m)~1岁(y)、1~2岁(y)、2~3岁(y)。末梢血Zn、Fe、Ca等3种微量元素采用BH5100型原子吸收光谱仪检测。结果研究组与对照组婴幼儿各年龄组其血Zn、Fe、Ca等微量元素水平的均值与正常参考值相比均在正常范围之间,其中研究组婴幼儿部分年龄组Zn和Ca元素水平高于非双胞胎婴幼儿,差异具有统计学意义(P<0.05),Fe元素则各年龄组均高于非双胞胎婴幼儿,差异具有统计学意义(P<0.05)。研究组与对照组各年龄组其微量元素水平存在偏低率和偏高率,其中:(1)Zn元素,研究组1岁以下的偏高率低于对照组,差异具有统计学意义(P<0.05),研究组1~3岁偏高率高于对照组,差异具有统计学意义(P<0.05);(2)Fe元素,研究组2~3岁的偏高率高于对照组,差异具有统计学意义(P<0.05);(3)Ca元素,研究组1~2岁偏低率低于对照组,2~3岁其偏低率高于对照组,差异具有统计学意义(P<0.05)。结论双胞胎婴幼儿其血Zn、Fe、Ca等微量元素均值均在正常参考值,但其正常值以及偏低率和偏高率的变化与非双胞胎婴幼儿相比均存在显著差异。Objective To study the changes of trace elements in 371 pairs of twin infants and young children. Methods A total of 371 pairs of twins from January 2016 to June 2017 were selected as the study group. 2 123 non-polyfetuses infants from January 2016 to June 2017 were randomly selected as control group. According to the age, the study group and the control group were divided into 5 groups: 5~6 months (m), 7~11 months (m), 12 months (m) ~ 1 year (y), 1~2 years (y), and 2~3 years (y). The 3 kinds of trace elements such as Zn, Fe and Ca in peripheral blood were detected by BH5100 atomic absorption spectrometer. Results The average level of blood Zn, Fe, Ca and other trace elements in the study group and the control group were in the normal range compared with the normal reference value. The level of Zn and Ca in the part age group of the study group was higher than that of the non-twin infants, the difference was statistically signifcant (P 〈 0.05). Fe elements were higher in all age groups than in non twin infants, and the difference was statistically signifcant (P 〈 0.05). There was a low and high rate of trace elements in the study group and the control group, of which: (1) Zn element, the high rate under 1 years of age in the study group was lower than that of the control group, the difference was statistically signifcant (P 〈 0.05). The high rate of the study group was higher than that of the control group at 1~3 years old (P 〈 0.05). (2) Fe was higher in the study group than in the control group at 2~3 years old (P 〈 0.05). (3) Ca element, the low rate of 1~2 years old in the study group was signifcantly lower than that in the control group, and the low rate of 2~3 years old group was higher than that of the control group, the difference was statistically significant (P 〈 0.05). Conclusion For the twins infants and young children,the average values of trace elements such as zinc, iron and calciumin were all in normal ra
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