全程营养护理管理对鼻咽癌放疗患者生活质量的影响研究  

Effects of whole-course nutritional nursing on life quality of patients with nasopharyngeal carcinoma during radiotherapy

作　　者：孙仁娟[1] 周乐源[1] 戴立芬 夏蓓南 吴平[1] 卞芸 徐梅琴 SUN Renjuan, ZHOU Yueyuan, DAI Lifen(Department of Internal Pediatrics, The Fourth People＇ s Hospital of Wuxi City, Affiliated Hospital of Jiangnan University,Jiangsu, Wuxi 214062, Chin)

机构地区：[1]江苏省无锡市第四人民医院江南大学附属医院内儿科,214062

出　　处：《河北医药》2018年第16期2550-2553,共4页Hebei Medical Journal

基　　金：无锡市医院管理中心2015年度医学科研面上项目(编号:YGZXM1516)

摘　　要：目的探讨全程营养护理管理模式对鼻咽癌放疗患者生活质量的影响。方法选取2015年7月至2017年1月收治的鼻咽癌患者120例作为研究对象,按照护理方式分为试验组和对照组,每组60例。对照组采用常规护理,试验组给予全程营养护理管理。比较试验组与对照组在入院时和疗程结束后的PG-SGA量表分组情况、EORTC QLQ-30生活质量评分、RTOG/EORTC急性放射反应情况以及与营养相关的实验室指标。结果试验组[PGSGA(B)]者较对照组多,[PG-SGA(C)]者较对照组少,且差异有统计学意义(P<0.05)。(2)试验组在功能领域(82.50±7.29 vs 62.85±6.18)、整体生活质量领域(61.59±5.42 vs 47.36±5.09)、症状领域(21.58±2.64 vs 29.37±2.77)和单项测量项目(20.15±2.33 vs 28.64±2.88)上的评分均与对照组差异有统计学意义(P<0.05)。试验组的皮肤反应和粘膜炎发生率均低于对照组,差异有统计学意义(P<0.05)。放疗结束后,对照组各项相关实验室指标均下降,与试验组相比,差异有统计学意义(P<0.05)。结论全程营养护理能够有效地提高鼻咽癌放疗患者的生活质量,可尝试进一步推广。Objective To explore the effects of whole-course nutritional nursing on life quality of the patients with nasopharyngeal carcinoma（ NPC） during radiotherapy. Methods A total of 120 patients with NPC who were admitted and treated in our hospital from July 2015 to January 2017 were randomly divided into experimental group（ n = 60） and control group（ n = 60） according to different nursing methods. The patients in control group were treated by conventional nursing care,however,the patients in experimental group were treated by whole-course nutritional nursing management. The PG-SGA scale,EORTC QLQ3. 0（ quality of life score）,RTOG/EORTC（ acute radiation reaction） and nutrition-related laboratory indexes（ ALB,PA,Hb,WBC and LC） of patients on admission and at the end of treatment were observed and compared between the two groups. Results The PG-SGA（ B） in experimental group were significantly more than those in control group,however,PG-SGA（ C） in experimental group were significantly less than those in control group（ P〈0. 05）. There were significant differences in function scores（ 82. 50 ± 7. 29 vs 62. 85 ± 6. 18）,whole life quality scores（ 61. 59 ± 5. 42 vs 47. 36 ± 5. 09）,the symptom scores（ 21. 58 ± 2. 64 vs 29. 37 ± 2. 77） and single item measurement scores（ 20. 15 ± 2. 33 vs 28. 64 ± 2. 88）between in experimental group and control group（ P〈0. 05）. Moreover the incidence rates of skin reactions and mucositis in experimental group were significantly lower than those in control group（ P〈0. 05）. At the end of radiotherapy,the related laboratory indexes in control group were significantly decreased,as compared with those in experimental group（ P〈0. 05）.Conclusion Whole-course nutritional nursing can improve significantly the life quality of patients with NPC during radiotherapy,which is worth using widely in clinical practice.

关 键 词：全程营养护理 鼻咽癌 放疗 生活质量 

分 类 号：R473.73[医药卫生—护理学]