腰椎间盘退变的T2~*mapping定量分析  

Quantitative Assessment of Lumbar Intervertebral Disk Degeneration by Using T2~*mapping

作　　者：周洁[1] 詹勇[1] 张衡 李钦海 向子云[1] ZHOU Jie;ZHAN Yong;ZHANG Heng;LI Qinhai;XIANG Ziyun(Department of Diagnostic Radiology,Shenzhen Longgang People’ Hospital,Shenzhen Guangdong 518172,China)

机构地区：[1]深圳市龙岗区人民医院影像科,广东深圳518172

出　　处：《中国医疗设备》2018年第8期83-86,共4页China Medical Devices

基　　金：深圳市科技计划项目(JCYJ20150402164314701);深圳市龙岗区科技发展资金项目(YLWS20150513163259372)

摘　　要：目的探讨1.5 T MRI T2*mapping成像定量评估腰椎间盘退变的可行性及其诊断价值。方法对195例腰腿痛患者行腰椎常规磁共振扫描及矢状位T2*mapping成像,并应用AW4.5工作站进行数据处理,采用Pfirrmann标准对纳入研究的732个椎间盘进行退变分级,定量分析不同分级间椎间盘的T2*值变化特点,分析T2*值与椎间盘退变分级间的相关性。结果 732个椎间盘中,PfirrmannⅠ级26个(3.6%)、Ⅱ级47个(6.4%)、Ⅲ级233个(31.8%)、Ⅳ级390个(53.3%)、Ⅴ级36个(4.9%)。腰椎间盘髓核及纤维环T2*值均随分级增加而减小;除Ⅰ级与Ⅱ级椎间盘髓核及纤维环、Ⅱ级与Ⅲ级纤维环T2*值差异无统计学意义(P>0.05),其余各级间差异均有统计学意义(P<0.05)。椎间盘髓核及纤维环T2*值与Pfi rrmann分级呈负相关(r=-0.68,P<0.05;r=-0.54,P<0.05)。结论 1.5 T MRI T2*mapping能对腰椎间盘退变进行客观、定量评估,腰椎间盘T2*值与Pfi rrman分级负相关。Objective To investigate the clinical value of T2＊mapping in detecting lumbar intervertebral disk degeneration （IVDD）. Methods T2WI, T1WI and T2＊mapping were scanned in 195 patients with low back pain. All data were transfered to the AW4.5 workstation for processing. According to Pfrrmann standard, 732 lumbar intervertebral discs were graded. T2＊ values of lumbar intervertebral discs in different grades were measured and quantitativly analyzed. Correlations between T2＊ values and Pfrrmann grades were further tested. Results Totally 732 intervertebral discs were fnally selected in the study, including 26 in gradeⅠ, 47 in in gradeⅡ, 233 in grade Ⅲ, 390 in grade Ⅳ, and 36 in grade Ⅴ. T2＊ values of intervertebral discs decreased while the IVDD grade increased. Significant differences of T2＊ values of NP or AF were found between different grades （P〈0.05） except that between gradeⅠandⅡ, and gradeⅡand Ⅲ. T2＊ values of nucleus pulposus （NP） and annulus fbrosus （AF） were negatively correlated with the Pfrrmann grades. Conclusion T2＊ mapping at 1.5 T MRI can objectively and quantitatively evaluate the degeneration of the lumbar intervertebral disc. T2＊ values of the lumbar intervertebral disc were negatively related to the Pfrrman grades.

关 键 词：腰椎 磁共振成像 椎间盘退变 MRI T2＊mapping成像 

分 类 号：R681.53[医药卫生—骨科学] R455.2[医药卫生—外科学]