实时右心声学造影对卵圆孔未闭相关偏头痛的观察  

Exploratory Research on Migraine Related with Patent Foramen Ovale by Real-time Contrast Echocardiography of Right Heart

作　　者：王嶒 张健[1] 范小明[1] 王静[1] 孙婷婷 FANG Ceng;ZHANG Jian;FAN Xiao-ming(Zhejiang Provincial People＇s Hospital,Zhejiang 310014,China)

机构地区：[1]浙江省人民医院(杭州医学院附属人民医院)超声科,310014

出　　处：《心脑血管病防治》2018年第3期192-195,共4页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

基　　金：浙江省中医药优秀青年人才基金项目(编号:2018ZQ005);浙江省医药卫生计划(编号:2017KY020);浙江省教育厅一般科研项目(编号:Y201738347)

摘　　要：目的对比分析经颅多普勒发泡实验、常规超声心动图右心声学造影技术对卵圆孔未闭的诊断,初步探讨卵圆孔未闭与不明原因的偏头痛之间的关系。方法选取我院排除其它原因所引起的偏头痛患者80例,对比研究经颅多普勒发泡实验、右心声学造影两种检查方法,观察有无出现右向左分流并对微气泡数量进行半定量的分级,后将两种方法与术中资料相比较。结果在卵圆孔未闭诊断中,右心声学造影的灵敏度、特异度、符合诊断率等指标均高于经颅多普勒发泡实验。右心声学造影不同组间的左心房内径越大,压力越大,右向左分流量越小。结论右心声学造影操作简便、安全可靠,在不明原因的偏头痛疾病的诊断中优势显著,具有较高的临床实用价值。Objective To analyze transcranial doppler foaming experiment and contrast echocardiography of right heart based on the conventional echocardiography to diagnose patent foramen ovale and the relationship between patent foramen ovale and unexplained migraine. Methods 80 cases of patients with migraine caused by other causes in our hospital were collected to study preoperative transcranial doppler foaming experiment and contrast echocardiography of right heart,and to observe the presence of a right-to-left shunt and half quantitative classification on the micro bubble number. Then the two methods were compared with the data in the operation. Results For the diagnosis of the patent foramen ovale,the sensitivity,specificity,diagnostic rate and other indicators of contrast echocardiography of right heart were all higher than those of transcranial doppler（ TCD） foaming experiment. Among the different groups of contrast echocardiography of right heart,the larger the left atrial diameter was,the greater the pressure was and the smaller the shunt was. Conclusions Contrast echocardiographyof right heart is simple and safe,and the diagnosis is remarkable,which has a high clinical practical value for further research of the unexplained migraine disease.

关 键 词：右心声学造影 卵圆孔未闭 右向左分流 

分 类 号：R541.1[医药卫生—心血管疾病] R747.2[医药卫生—内科学]