常熟地区非结核分支杆菌肺病与耐药肺结核及其一线药物耐药分析  

Analysis of non-tuberculous mycobacteria lung disease and drug-resistant tuberculosis and its first-line drug resistance in Changshu

作　　者：陈健[1] 王译 韦海旭[1] 席薇莲[1] 陆利欢[1] 王志毅 CHEN Jian;WANG Yi;WEI Hai-xu;XI Wei-Lian;LU Li-Huan;WANG Zhi-yi(Department of infectious diseases,Second People＇s Hospital,Changshou City,Jiangsu Suzhou 215500,China)

机构地区：[1]常熟市第二人民医院传染病分院肺科,江苏苏州215500

出　　处：《临床医药文献电子杂志》2018年第42期23-24,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的分析痰菌阳性患者抗结核治疗2月后痰菌仍为阳性原因,探讨导致抗结核治疗效果不佳中非结核分支杆菌(NTM)肺病占比及其对常用一线药物耐药比例分析,提高对NTM肺病的认识。方法研究2012年5月~2017年5月初治菌阳患者抗结核治疗2月仍未转阴患者痰结核菌培养菌种鉴定及药敏试验共137例。结果非结核分支杆菌肺病(NTM)患者占20例,占比14.60%,人型结核分支杆菌为117例,占比85.40%。结论非结核分支杆菌成为菌阳结核患者中治疗效果不佳的重要原因之一,其比例几乎与耐药结核相当。Objective This paper is about to analyze the positive cause of anti-tuberculosis treatment in sputum-positive patients after 2 months, and to explore the proportion of non-tuberculosis mycobacteria（NTM） lung disease and its resistance to common first-line drugs,in order to improve the understanding of NTM lung disease.Methods Analyze 137 cases of antimicrobial susceptibility test of the patients who were treated with anti-tuberculosis for 2 months without turning to negative.Results 20 cases（14.60%） of nontuberculosis mycobacteria（NTM） patients;117 cases（85.40%） of Human tuberculosis Mycobacterium tuberculosis.Conclusion Mycobacterium tuberculosis is one of the most important causes of poor treatment in patients with tuberculosis. Its proportion is almost the same as that of drug-resistant tuberculosis.

关 键 词：非结核分枝杆菌肺病 NTM 耐药 

分 类 号：R521[医药卫生—内科学]