运动干预改善聋哑儿童执行控制的多模态磁共振研究  

Effects of Exercise Intervention on Executive Control in Deaf Children:A Multimodal Magnetic Resonance Imaging Research

作　　者：陈爱国[1,2] 董晓晓 朱丽娜 熊轩[1,2] CHEN Aiguo;DONG Xiaoxiao;ZHU Lina;XIONG Xuan(School of Physical Education,Yangzhou University,Yangzhou 225127,China;Sports and Brain Re search Institute,Yangzhou University,Yangzhou 225127,China)

机构地区：[1]扬州大学体育学院,扬州225127 [2]扬州大学体育运动与脑科学研究所,扬州225127

出　　处：《体育与科学》2018年第4期52-59,共8页Sports & Science

基　　金：国家自然科学基金资助项目<有氧运动促进儿童执行功能发展的脑网络机制研究>;项目号:31771243;霍英东教育基金会基金<基于多模态磁共振成像技术追踪研究有氧运动对儿童脑执行功能区的影响>;项目号:141113;江苏省"青蓝工程"资助;扬州大学教学改革研究课题<促进大学生执行功能发展的体育教学改革研究>;项目号:YZUJX2016-15B

摘　　要：目的:采用多模态磁共振技术探讨运动干预所致聋哑儿童脑结构和功能可塑性的变化,为揭示运动干预改善聋哑儿童执行控制的神经机制提供新的证据。方法:分别从两所特殊教育学校筛选26名聋哑儿童,随机分为实验组和对照组,实验组进行11周"花样跳绳+武术操+花样跑步"运动方案干预,对照组在实验期间进行常规活动。分别采用Flanker任务、结构磁共振成像技术(structural magnetic resonance imaging,sMRI)以及静息态功能磁共振成像技术(resting-state functional magnetic resonance imaging,rs-fMRI)考察聋哑儿童运动干预前、后的执行控制行为表现、脑灰质体积和功能连接的变化。结果:(1)运动干预促进了聋哑儿童执行控制的行为表现[F(1,14)=7.67,P<0.01,partialη~2=0.35];(2)运动干预诱发聋哑儿童右侧顶上回[F(1,14)=4.64,P<0.05,partialη~2=0.25]、右侧壳核[F(1,14)=4.60,P=0.05,partialη~2=0.25]以及右侧苍白球[F(1,14)=8.36,P<0.05,partialη~2<0.37]的灰质体积增加;(3)运动干预诱发聋哑儿童右侧顶上回与右侧中央前回[F(1,14)=5.28,P<0.05,partialη~2=0.27]、右侧顶上回与左侧颞中回[F(1,14)=11.07,P<0.01,partialη~2=0.44]、右侧顶上回与右侧颞中回[F(1,14)=5.30,P<0.05,partialη~2=0.28]、右侧苍白球与左侧眶部额下回[F(1,14)=4.86,P<0.05,partialη~2=0.26]的功能连接减弱。结论:运动干预可以改善聋哑儿童执行控制,其原因在于运动干预所致的灰质体积增加以及伴随的相关脑区功能连接的重组。Objective：To investigate the effect of exercise intervention on executive control and the changes of brain plasticity in deaf children using multimodal magnetic resonance imaging,and further explore the neural basis of exercise intervention on executive control in deaf children.Methods：Twenty-six deaf children,recruited from two special education schools,were randomly assigned into control or exercise group.The exercise group was offered an after-school exercise program at moderate intensity for 11weeks.All participants were subjected to complete a Flanker task and brain scans both at baseline and after intervention for detecting changes of executive control behavior performance and brain plasticity,based on the voxel-based morphometry（VBM）and restingstate functional connectivity（FC）.Results：Compared with the no-intervention,the exercise intervention benefitted performance in the Flanker task,increased gray matter volume in the right Superior parietal gyrus[F（1,14）=4.64,P〈0.05,partialη^2=0.25],right putamen[F（1,14）=4.60,P=0.05,partialη^2=0.25],right pallidum[F（1,14）=8.36,P〈0.05,partialη^20.37],decreased functional connectivity including right Superior parietal gyrus and right Precental gyrus[F（1,14）=5.28,P〈0.05,partialη^2=0.27],right Superior parietal gyrus and left Middle temporal gyrus[F（1,14）=11.07,P〈0.01,partialη^2=0.44],right Superior parietal gyrus and right Middle temporal gyrus[F（1,14）=5.30,P〈0.05,partialη^2=0.28],right pallidum and left inferior frontal gyrus,orbital part,[F（1,14）=4.86,P〈0.05,partialη^2=0.26].Conclusion：These data extended the current knowledge by indicating that exercise intervention enhanced deaf children’s executive control,which the neural basis may be related to the increment in gray matter volume and the decrement in functional connectivity by exercise intervention.

关 键 词：运动干预 聋哑儿童 执行控制 多模态磁共振 

分 类 号：G80-05[文化科学—运动人体科学]