宁波社区2型糖尿病患者发生糖尿病肾病危险因素调查  

A community-based survey on risk factors of type 2 diabetic kidney disease in Ningbo,China

作　　者：李小勇[1] 沈鹏[1] 林鸿波[1] 虞哲彬 陈坤[2] 王建炳 LI Xiaoyong;SHEN Peng;LIN Hongbo;YU Zhebin;CHEN Kun;WANG Jianbing(Department of Health Education and Chronic Disease Control,Ningbo Yinzhou District Center for Disease Control and Prevention,Ningbo 315040,Zhejiang Province,China;School of Public Health,Zhejiang University School of Medicine,Hangzhou 310058,China)

机构地区：[1]宁波市鄞州区疾病预防控制中心健康教育与慢性病防治科,浙江宁波315040 [2]浙江大学医学院公共卫生系,浙江杭州310058

出　　处：《浙江大学学报（医学版）》2018年第2期163-168,共6页Journal of Zhejiang University(Medical Sciences)

基　　金：浙江省医药卫生科技计划(2015124340)

摘　　要：目的:调查宁波市鄞州区2型糖尿病患者糖尿病肾病的发生率,并分析2型糖尿病患者发生糖尿病肾病的危险因素。方法:收集浙江省宁波市鄞州区所有在册管理且开展过糖尿病肾病筛查的2型糖尿病患者的人口学、临床检测信息、糖尿病合并症和行为危险因素等信息,利用logistic回归分析筛选糖尿病肾病发生的危险因素。结果:本研究共纳入糖尿病患者10 604例,其中发生糖尿病肾病3744例(35.31%)。单因素分析结果显示,糖尿病肾病发生的风险可能与患者的性别、年龄、文化程度、糖尿病病程、血糖控制情况、是否合并高血压、是否合并脑卒中、是否吸烟和腰围等因素相关(P<0.05或P<0.01)。多因素logistic回归分析结果显示,男性、高龄、糖尿病病程长、合并高血压、吸烟等因素可能是糖尿病肾病发生的危险因素(P<0.05或P<0.01)。结论:宁波市鄞州区2型糖尿病患者糖尿病肾病的发生率较高。男性、高龄、吸烟、糖尿病病程长、合并高血压可能会增加糖尿病患者发生糖尿病肾病的风险。Objective： To investigate the prevalence and risk factors of diabetic nephropathy in Ningbo Yinzhou district. Methods： Nephropathy screening was conducted among patients with type 2 diabetes mellitus（ T2 DM） registered in Ningbo Yinzhou district. Demographic information,clinical examination information,diabetes complications and behavioral risk factors of enrolled patients were collected. Logistic regression model was used to identify possible risk factors for the occurrence of diabetic nephropathy. Results： Among 10 604 T2 DM patients included in this study,there were3744 cases of diabetic nephropathy（ 35. 31%）. Univariate analysis showed that gender,age, education level, diabetes duration, glycemic control, hypertension, stroke,smoking and waist circumference were associated with diabetic nephropathy（ P〈0. 05 or P〈0. 01）. Multivariate logistic regression analysis showed that male,elders,long diabetes duration,hypertension and smoking were independent risk factors of diabetic nephropathy（ P〈0. 05 or P〈0. 01）. Conclusions： Diabetic nephropathy is of high prevalence in T2 DM patients. Male patients,elders,and those with long diabetes duration,hypertension and smoking habits are more likely to have diabetic nephropathy.

关 键 词：糖尿病 2型/并发症 糖尿病肾病/病因学 危险因素 LOGISTIC模型 比值比 血压 吸烟 

分 类 号：R587.2[医药卫生—内分泌] R195.4[医药卫生—内科学]