1例乙型肝炎患者接触二甲基甲酰胺中毒报告  

A case report of hepatitis B combined with dimethylformamide poisoning

作　　者：张海蕾[1] 王金富 李颖芳 方家阳 张美辨[4] ZHANG Hai-lei;WANG Jin-fu;LI Ying-fang;FANG Jia-yangl;ZHANG Mei-bian(Environmental and Occupational Health Department,Taizhou Center for Disease Control and Prevention,Taizhou,Zhejiang 318000,China;Patriotic Health Campaign Office,Taizhou City Health and Family Planning Commission,Taizhou,Zhejiang 318000,China;Office,Yongdeng Qilianshan Cement Co.,Ltd.,Yongdeng,Gansu 730300,China;Environmental and Occupational Health Department,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)

机构地区：[1]台州市疾病预防控制中心环境与职业卫生科,浙江台州318000 [2]台州市卫生与计划生育委员会爱国卫生运动办公室,浙江台州318000 [3]永登祁连山水泥有限公司办公室,甘肃永登730300 [4]浙江省疾病预防控制中心环境与职业卫生所,浙江杭州310051

出　　处：《环境与职业医学》2018年第7期661-664,共4页Journal of Environmental and Occupational Medicine

基　　金：浙江省卫生高层次创新人才培养工程项目(编号:浙卫发[2016]63号)

摘　　要：某乙肝患者在未进行岗前职业健康检查的情况下从事接触二甲基甲酰胺(DMF)作业,作业岗位空气中DMF浓度符合国家接触限值要求,但仍发生中毒事件,且病情严重,不排除乙型肝炎与DMF中毒两种病因交叉作用或协同作用的可能性。该病例诊断过程提示用人单位须重视职业卫生管理,履行职业病防治主体责任,做好上岗前职业健康检查,及时发现职业禁忌症,减少DMF接触机会,防止类似中毒事件的发生;职业卫生监管部门应加强对用人单位的监督管理,督促其履行职业病防治主体责任。A case of severe occupational dimethylformamide （DMF） poisoning was reported. The worker was diagnosed as hepatitis B without pre-employment occupational health examination and exposed to DMF meeting the requirements of national exposure limits. No evidence supported to eliminate the potential interaction or synergistic effect between hepatitis B and DMF poisoning. The diagnosis process suggested that DMF exposure and similar poisoning incidents might be prevented through employers＇ attaching importance to occupational health management, fulfilling the principle responsibility for occupational disease prevention and treatment, performing pre-employment occupational health examinations, and timely detecting occupational contraindications; occupational health supervision departments should strengthen the supervision and management to employers, urging them to fulfill the principle responsibility for prevention and treatment of occupational diseases.

关 键 词：二甲基甲酰胺 乙型肝炎 中毒 

分 类 号：R135.1[医药卫生—劳动卫生]