诱导型与转基因型类风湿性关节炎模型的研究进展  

Research progress of induced and transgenic rheumatoid arthritis model

作　　者：范凯健 吴菁[2] 李允武[2] 王婷玉[2] FAN Kai-jian;WU Jing;LI Yun-wu;WANG Ting-yu(Department of Pharmacy,Shanghai Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 201901,China;Department of Pharmacy,Shanghai Ninth People＇ s Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200011,China)

机构地区：[1]上海市宝山区中西医结合医院药剂科,上海201901 [2]上海交通大学医学院附属第九人民医院药剂科,上海200011

出　　处：《实用药物与临床》2018年第6期709-713,共5页Practical Pharmacy and Clinical Remedies

基　　金：国家自然科学基金(81301531;81572104)

摘　　要：类风湿性关节炎模型对研究类风湿性关节炎发病机制和评价药物治疗效果具有非常重要的作用。本文通过检索国内外文献,对最常用的几种类风湿性关节炎模型的研究进展进行介绍,以期为实验选用合理的模型和深入研究类风湿性关节炎的发病机制提供依据。The model of rheumatoid arthritis is very important to the study of the pathogenesis of rheumatoid arthritis and the evaluation of drug treatment. The research progress of the most common types of the models of rheumatoid arthritis was introduced by searching domestic and foreign literature. This review aims to provide a basis for the selection of rational models and the study of the pathogenesis of rheumatoid arthritis.

关 键 词：类风湿性关节炎 诱导型 转基因型 动物模型 发病机制 

分 类 号：R593.22[医药卫生—内科学]