苯扎氯铵在犬咬伤伤口清创中的应用效果观察  

Benzalkonium chloride in debridement of dog bite wounds

作　　者：贾亿卿[1] 陈瑞丰[1] 黄立嵩[1] 王雪飞[1] 刘玉杰 黄超[1] 单毅[1] JIA Yiqing;CHEN Ruifeng;HUANG Lisong;WANG Xuefei;LIU Yujie;HUANG Chao;SHAN Yi(Department of Emergency,Navy General Hospital,Beijing 100048,China)

机构地区：[1]海军总医院急诊科,北京100048

出　　处：《解放军医学院学报》2018年第7期618-620,共3页Academic Journal of Chinese PLA Medical School

摘　　要：目的探讨苯扎氯铵溶液在处理犬咬伤伤口中的临床应用效果。方法将2016年12月-2017年12月于我院急诊外科就诊的378例犬咬伤患者随机分为实验组(n=188)和对照组(n=190)。实验组应用碘伏溶液联合苯扎氯铵溶液处置伤口,对照组采用常规的碘伏溶液处置伤口。观察并记录对伤口处置时疼痛指数及伤口愈合感染率。结果实验组相比对照组伤口疼痛明显减轻(NPRS:2.87±0.94 vs 5.98±1.01,P=0.000 1),实验组的感染率明显低于对照组(7.43%vs 14.21%,P=0.021)。结论采用苯扎氯铵溶液冲洗伤口,可减轻患者疼痛,有较好的抗感染效果。Objective To explore the clinical effect of benzalkonium chloride solution in the treatment of dog bite wounds. Methods Three hundred and seventy-eight patients suffering from dog bite wounds admitted to our hospital from December 2016 to December 2017 were divided randomly into the experimental group （n=188） and control group （n=190）. The wounds of patients in experimental group were treated with iodophor solution along with benzalkonium chloride solution, while the wounds of the control group were treated with iodophor solution as usual. The pain index and rates of wounds infection were observed and documented.Results Compared with control group, the pain index and the infection rate of experimental group were significantly lower （2.87±0.94 vs 5.98±1.01, P =0.000 1; 7.43% vs 14.21%, P =0.021）. Conclusion Using benzalkonium chloride solution to wash the wound can relieve pain, an achieves better anti infection outcome.

关 键 词：苯扎氯铵 犬咬伤 清创 

分 类 号：R646[医药卫生—外科学]