Multi-stability involved mixed bursting within the coupled pre-Btzinger complex neurons  

作　　者：Zijian Wang Lixia Duan Qinyu Cao 王子剑;段利霞;曹秦禹(School of Science, North China University of Technology, Beijing 100144, China)

机构地区：School of Science,North China University of Technology,Beijing 100144,China

出　　处：《Chinese Physics B》2018年第7期227-233,共7页中国物理B（英文版）

基　　金：Project supported by the National Natural Science Foundation of China(Grant No.11472009);Construction Plan for Innovative Research Team of North China University of Technology(Grant No.XN018010);Scientific Research for Undergraduate of North China University of Technology

摘　　要：Neurons in the pre-B6tzinger complex within the mammalian brain stem play important roles in the generation of respiratory rhythms. Experimental observations show that some neurons can exhibit novel mixed bursting activities. In this paper, based on a mathematical model proposed by Butera, we show how the mixed bursting activities depend on the potassium current in the coupled pre-Botzinger complex. Using fast-slow decomposition and bifurcation analysis, we investigate the dynamics of mixed bursting, as well as the mechanisms of transition between different mixed bursting patterns. We find that mixed bursting involves different bistability, and it is the transition state of two types of regular burstings.Neurons in the pre-B6tzinger complex within the mammalian brain stem play important roles in the generation of respiratory rhythms. Experimental observations show that some neurons can exhibit novel mixed bursting activities. In this paper, based on a mathematical model proposed by Butera, we show how the mixed bursting activities depend on the potassium current in the coupled pre-Botzinger complex. Using fast-slow decomposition and bifurcation analysis, we investigate the dynamics of mixed bursting, as well as the mechanisms of transition between different mixed bursting patterns. We find that mixed bursting involves different bistability, and it is the transition state of two types of regular burstings.

关 键 词：pre-Botzinger complex fast-slow decomposition BIFURCATION mixed bursting 

分 类 号：Q42[生物学—神经生物学]