Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer  

作　　者：成明洙 Phuong Minh Mai 李基準 金載官 

机构地区：[1]Department of Biomedical Science and Engineering, Institute of Integrated Technology, Gwangju Institute of Science and Technology, Gwangju 61005, Korea [2]School of Electrical Engineering and Computer Science,Gwangju Institute of Science and Technology, Gwangju 61005, Korea [3]School of Undergraduate Studies, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Korea

出　　处：《Chinese Optics Letters》2018年第7期60-64,共5页中国光学快报（英文版）

基　　金：partially supported by the SGER grant NRF-2015R1D1A1A02062382(J.G.Kim);Global Ph.D.Fellowship Program NRF-2015H1A2A1032268(M.Seong)through the National Research Foundation of Korea(NRF) funded by the Ministry of Education;GIST Research Institute in 2018

摘　　要：Blood oxygenation and flow are both important parameters in a living body. In this Letter, we introduce a simple configuration to simultaneously measure blood flow and oxygenation using an off-the-shelf spectrometer. With the integration time of 10 ms, flow phantom measurements, a liquid blood phantom test, and an arm cuff occlusion paradigm were performed to validate the feasibility of the system. We expect this proof-of-concept study would be widely adopted by other researchers for acquiring both blood flow and oxygenation changes due to its straightforward configuration and the possibility of multimodal measurement.Blood oxygenation and flow are both important parameters in a living body. In this Letter, we introduce a simple configuration to simultaneously measure blood flow and oxygenation using an off-the-shelf spectrometer. With the integration time of 10 ms, flow phantom measurements, a liquid blood phantom test, and an arm cuff occlusion paradigm were performed to validate the feasibility of the system. We expect this proof-of-concept study would be widely adopted by other researchers for acquiring both blood flow and oxygenation changes due to its straightforward configuration and the possibility of multimodal measurement.

关 键 词：Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer BFI 

分 类 号：O657.3[理学—分析化学] R318.6[理学—化学]