壮族地区孕前体质指数、孕期增重及孕期贫血对小于胎龄儿影响研究  

Impact of maternal pre-pregnant body mass index,gestational weight gain and pregnant anemia on SGA in Zhuang Region

作　　者：邵炎涛 黄东萍 刘顺[1] 黄倩 卢美菊 郭雪峰[1] 陈洁华[1] 仇小强[1] SHAO Yan-tao;HUANG Dong-ping;LIU Shun;HUANG Qian;LU Mei-ju;GUO Xue-feng;CHEN Jie-hua;QIU Xiao-qiang(Department of Epidemiology and Health Statistics,School of Public Health,Guangxi Medical University,Nanning 530021,China;Department of Hygiene Chemistry,School of Public Health,Guangxi Medical University,Nanning 530021,China;Department of Maternity,Pingguo County People's Hospital,Baise 531400,China;Department of Maternity,Pingguo County Maternal&Child Hospital,Baise 531400,Chin)

机构地区：[1]广西医科大学公共卫生学院流行病与卫生统计学教研室,广西南宁530021 [2]广西医科大学公共卫生学院卫生化学教研室,广西南宁530021 [3]广西平果县人民医院产科,广西百色531400 [4]广西平果县妇幼保健院产科,广西百色531400

出　　处：《中华疾病控制杂志》2018年第7期663-666,共4页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(81460517);广西科技计划项目(桂科AB17195012)

摘　　要：目的分析壮族地区小于胎龄儿(small for gestational age infants,SGA)发生情况,探讨孕妇孕前体质指数(body mass index,BMI)、孕期增重及孕期贫血等因素对发生SGA的影响,为更好地开展孕期保健指导提供依据。方法选取2016年1~12月在广西平果县及隆安县的三家医院产科门诊首次产检、孕6~13周的2 199例单胎妊娠孕妇,收集孕妇的基本信息,并随访其产检记录、妊娠结局等信息。使用t检验、χ~2检验和Logistic回归模型对调查数据进行分析。结果 SGA共327例,发生率为14.87%。调整混杂因素后,孕前BMI<18.5 kg/m^2的孕妇比孕前BMI正常孕妇SGA发生风险增加1.09倍(OR=2.09,95%CI:1.59~2.75,P<0.001),孕期体重增加不足孕妇比增加正常孕妇SGA发生风险增加1.19倍(OR=2.19,95%CI:1.67~2.86,P<0.001),孕期轻、中重度贫血对SGA发生风险的影响差异均无统计学意义(均有P>0.05)。结论孕前体质指数<18.5 kg/m^2和孕期增重不足为该地区孕妇分娩SGA的危险因素。Objective To analyze the occurrence of small for gestational age infants （SGA） in Zhuang ethnicity region and the effects of pre-pregnant body mass index （BMI）, gestational weight gain and pregnant anemia on SGA, to provide rationa- le to develop better health care for pregnant women. Methods A total of 2 199 pregnant women of single pregnancy were select- ed as the participants, who received the first prenatal examination during the first 6 to 13 weeks of gestation in Pinggno People＇ s Hospital, Child Health Hospital and Long＇an People＇s Hospital from January to December 2016, data of the general conditions of pregnant women, regular prenatal examination records, the pregnancy outcomes etc were collected, t-test, Z2 test and Logistic regression model were used for statistical analysis. Results A total of 327 infants were SGA, and the incidence of SGA was 14. 87%. Mter adjusting the confounding factors, compared to the normal pre-pregnant BMI group, the pre-pregnant BMI 〈18. 5 kg/m2 group showed increased risk of SGA （ OR=2.09, 95% CI： 1.59-2. 75, P〈0. 001）, compared to the normal gestational weight gain group, women with insufficient gestational weight gain had increased risk of SGA （OR= 2. 19, 95% CI： 1.67- 2. 86, P〈0. 001） among their infants. There was no significant difference in the risk of pregnant anemia on SGA （all P〉 0. 05）. Conclusion Pre-pregnant BMI〈 18.5 kg/m2, insufficient gestational weight gain are risk factors for SGA in Zhuang ethnicity region.

关 键 词：孕前 体质指数 孕期增重 孕期贫血 小于胎龄儿 

分 类 号：R556[医药卫生—血液循环系统疾病]