中老年人腹部脂肪分布与糖尿病的关系  

Relationship between abdominal fat distribution and diabetes in middle-aged and old people

作　　者：倪雪峰 牟文兵 焦力 于康 李冬晶 Ni Xuefeng, Mou Wenbing, Jiao Li, Yu Kang, Li Dongjing.(Department of Health Care, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, Chin)

机构地区：[1]中国医学科学院北京协和医学院,北京协和医院保健医疗部,100730 [2]中国医学科学院北京协和医学院,北京协和医院放射科,100730

出　　处：《中华临床营养杂志》2018年第3期176-180,共5页Chinese Journal of Clinical Nutrition

基　　金：中央保健重点科研课题（W2015ZD03）

摘　　要：目的探讨中老年人腹部脂肪容积及分布与糖尿病或空腹血糖升高之间的关系。方法根据北京协和医院保健医疗部2015至2016年162例体检患者的腹部CT，计算其腹部脂肪容积与分布，分析腹部脂肪容积及分布的情况与糖尿病或空腹血糖升高之间的相关性。结果51-75岁人群，无糖代谢异常组与糖尿病或空腹血糖升高组相比，腹部内脏脂肪百分比明显偏低[（41.8±10.9）%比（46.9±10.9）%，t＝－2.346，P＝0.02]；而腹部内脏脂肪容积仅有减少趋势[（63.61±24.95）mm^3比（70.39±31.33）mm^3 ，t＝－1.229，P＝0.22]、腹部皮下脂肪容积有增多趋势[（89.03±32.94）mm^3比（83.18±43.25）mm^3，t＝1.070，P＝0.43]，差异无统计学意义；腹部脂肪总量[（152.64±46.84）mm^3比（151.84±61.32）mm^3,t＝0.076，P＝0.94]大致相同。76-100岁人群，无糖代谢异常组与有糖尿病或空腹血糖升高组相比，腹部内脏脂肪容积[（68.29±39.58）mm^3比（51.56±25.89）mm^3]、腹部皮下脂肪容积[（84.65±41.30）mm^3比（75.29±42.04）mm^3]、腹部脂肪总量[（152.96±69.92）mm^3比（126.86±62.13）mm^3]、腹部内脏脂肪百分比[（43.7±12.0）%比（41.1±11.8）%]均有升高趋势，但两组间差异均无统计学意义（t分别为1.885、0.839、1.479、0.810，P值分别为0.07、0.40、0.15、0.42）。结论在51-75岁人群，腹部内脏脂肪占腹部脂肪的百分比增高者更容易出现糖尿病或空腹血糖升高，而在76-100岁的人群，腹部脂肪的容积或分布与糖代谢异常没有明显的相关性。Objective A analyze the relation between abdominal fat and diabetes mellitus in elderly person aged 51- 100. Methods According to the abdominal CT scan in 2015 to 2016 of 162 patients in Peking Union Medical College Hospital, the volume and distribution of their abdominal fat were measured to analyze the relationship between abdominal fat and diabetes mellitus. Results People aged 51-75, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have less abdominal visceral fat [ （63.61±24.95） mm^3 vs. （70.39±31.33） mm^3 t=-1.229, P=0. 22], tend to have more abdominal subcutaneous fat [ （89.03±32.94） mm^3 vs. （83.18±43.25） mm^3, t= 1.070, P= 0.43）, but both are not significant difference, total abdominal fat is similar between the two group [ （152.64±46.84） mm^3 vs. （151.84±61.32） mm^3, t=0.076, P=0.94], abdominal visceral fat percentage is significantly lower [ （41.8±10. 9）% vs. （46. 9±10. 9）%, t=-2. 346, P=0. 02]. People aged 76-100, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have more abdominal visceral fat [ （68.29±39.58） mm^3 vs. （51.56±25.89） mm^3）, abdominal subcutaneous fat [ （84.65±41.30） mm^3 vs. （75.29±42.04） mm^3] , total abdominal fat [ （ 152.96±69.92） mm^3 vs. （ 126.86±62. 13） mm^3], abdominal visceral fat percentage [ （43.7±12）% vs. （41.1± 11.8）%], allofthem are not significant （t=1.885, 0.839, 1. 479, 0.810, respectively; P=0.07, 0.40, 0.15,0.42, respectively）. Conclusions In people aged 51-75, those who had increased ratio of abdominal visceral fat to total abdominal fat were more prone to diabetes or fasting hyperglycemia. In people aged 76- 100, no significant correlation was detected between abdominal fat and disorder of glucose metabolism.

关 键 词：糖尿病 2型 肥胖 皮下脂肪 内脏脂肪 

分 类 号：R587.1[医药卫生—内分泌]