心理干预对中晚期食管癌同期放化疗患者抑郁焦虑及生活质量影响  

Effects of Psychological Intervention on Depression,Anxiety and Quality of Life of Intermediate and Advanced Esophageal Cancer Patients Treated With Chemoradiotherapy

作　　者：李绵 王玉强[1] 齐增平[1] 路洪超[1] 赵卫林[1] 胡锋超[1] 乔钦增[1] LI Mian, WANG Yuqiang, QI Zengping, LU Hongchao, ZHAO Weilin, HU Fengchao, QIAO Qinzeng(Department of Medical Oncology of Civil Administration Hospital of Hebei Province, Xingtai 054000, Hebei Province, Chin)

机构地区：[1]河北省民政总医院,河北邢台054000

出　　处：《预防医学情报杂志》2018年第9期1131-1135,共5页Journal of Preventive Medicine Information

基　　金：河北省科学技术研究与发展计划项目(项目编号:162777275)

摘　　要：目的探索心理干预对中晚期食管癌同期放化疗患者抑郁、焦虑情绪及生活质量的影响。方法将2015-06/2016-12在河北省民政总医院肿瘤内科就诊的196例接受同期放化疗的中晚期食管癌患者作为研究对象,随机分为对照组98例和心理干预组98例,对照组患者于同期放化疗期时进行常规护理,心理干预组在对照组基础上给予心理干预,于治疗前后用抑郁自评量表(SDS)、焦虑自评量表(SAS)和生活质量量表(EORTC QLQ-C30)评价患者的抑郁、焦虑及生活质量。结果干预前两组患者SDS、SAS和EORTC QLQ-C30评分差异无统计学意义(P>0.05),干预后心理干预组患者SDS和SAS评分低于对照组(t值分别为12.595和23.226,P<0.01),整体生活质量、角色功能、认知功能、情绪功能评分高于对照组(t值分别为5.059、4.746、2.820和3.606,P<0.05),疲乏、疼痛、恶心呕吐、失眠、食欲丧失评分低于对照组(t值分别为5.213、3.005、3.620、3.381和4.223,P<0.05)。结论心理干预能够改善中晚期食管癌同期放化疗患者的抑郁和焦虑情绪,提高患者的生活质量。Objective To explore the effects of psychological intervention on depression,anxiety and quality of life of intermediate and advanced esophageal cancer patients treated with chemoradiotherapy. Methods The 196 intermediate and advanced esophageal cancer patients who received chemoradiotherapy in department of radiotherapy in Civil Administration Hospital of Hebei Province from June 2015 to December 2016 were selected as research objects. They were randomly divided into control group and psychological intervention group. There were 98 patients in each group. Patients in the control group received routine care during chemoradiotherapy.Patients in the psychological intervention group received psychological intervention on the basis of patients in the control group. Then we evaluated depression,anxiety and quality of life of patients with Self-Rating Depression Scale,Self-Rating Anxiety Scale and Quality of life questionnaire-core 30 before and after treatment. Results There were no statistically significant difference in SDS scores,SAS scores and EORTC QLQ-C30 scores between two groups of patients before intervention（ P 〉 0. 05）. SDS and SAS scores of patients in the psychological intervention group were lower than those in the controls group after intervention（ t = 12. 595/23. 226,P 〈0. 001）. The scores of the overall quality of life,role function,cognitive function,emotional function of patients in the psychological intervention group were higher than those in the controls group after intervention（ t= 5. 059/4. 746/2. 820,P 〈 0. 05）. The scores of fatigue,pain,nausea and vomiting,insomnia,loss of appetite were lower than those in the control group（ t = 5. 213/3. 005/3. 620/3. 381/4. 223,P 〈 0. 05）.Conclusion The depression and anxiety of intermediate and advanced esophageal cancer patients treated with chemoradiotherapy in the psychological intervention can be improved and their quality of life can be enhanced by psychological intervention.

关 键 词：心理干预 食管癌 抑郁 焦虑 生活质量 

分 类 号：R395[哲学宗教—心理学]