肾移植术后巨细胞病毒肺炎临床特点及危险因素分析  

Analyses for clinical characteristics and risk factors of cytomegalovirus pneumonia after renal transplantation

作　　者：范铁艳[1] 邱爽 陈虹[1] 沈中阳[1] Fan Tieyan;Qiu Shuang;Chen Hong;Shen Zhongyang(Organ Transplantation Institute,General Hospital of Chinese People＇s Armed Police Forces,Beijing 100039,China)

机构地区：[1]武警总医院器官移植研究所,北京100039

出　　处：《实用器官移植电子杂志》2018年第3期192-195,共4页Practical Journal of Organ Transplantation(Electronic Version)

摘　　要：目的探讨肾移植受者巨细胞病毒肺炎的临床特点,分析肾移植术后巨细胞病毒肺炎发生的危险因素。方法回顾性分析2005年6月—2017年8月武警总医院完成的1 598例次肾移植手术患者的临床资料,其中巨细胞病毒肺炎59例次,分析肾移植术后巨细胞病毒肺炎的临床特点及危险因素。结果肾移植术后巨细胞病毒肺炎发生率为3.7%,病死率为6.8%。Logistic回归结果显示CD4数量、激素大量使用是肾移植术后巨细胞病毒肺炎感染的危险因素。结论肾移植后巨细胞病毒肺炎的发生率高,免疫抑制过度可能是肾移植术后巨细胞病毒肺炎高发的危险因素。Objective To explore the clinical characteristics of cytomegalovirus pneumonia after renal transplantation. To analyze the risk factors of cytomegalovirus pneumonia after renal transplantation. Methods A total of 1 598 cases renal transplant patients in General Hospital of Chinese People ＇s Armed Police Forces from June 2005 to August 2017 were analyzed retrospectively. The clinical data of cytomegalovirus pneumonia of 59 cases renal transplant patients were collected. Clinical characteristics and risk factors of cytomegalovirus pneumonia after renal transplantation were analyzed. Results The incidence of cytomegalovirus pneumonia after renal transplantation was 3.7% and the mortality rate was 6.8%. CD4 lymphocyte count and steroid excess were risk factors of cytomegalovirus pneumonia after renal transplantation. Conclusion The incidence of cytomegalovirus pneumonia after renal transplantation was higher. The use of immunosuppressive agents maybe the main risk factors of cytomegalovirus pneumonia after renal transplantation.

关 键 词：肾移植 肺部感染 巨细胞病毒肺炎 

分 类 号：R563.1[医药卫生—呼吸系统] R699.2[医药卫生—内科学]