Protective Effect of Space Ginseng Yeast on Human Primary Fibroblasts under Simulated Microgravity Condition  

作　　者：Xiaojie SONG Xiaoting SHI Yue WU 

机构地区：[1]R&D Center,Jala Corporation

出　　处：《Medicinal Plant》2018年第4期87-90,共4页药用植物：英文版

摘　　要：[Objectives] To study the protective effect of Space Ginseng Yeast on human primary fibroblasts. [Methods] Multiple indicators were used to simulate the microgravity effect,so as to study the protective effect of Space Ginseng Yeast on human primary fibroblasts under simulated microgravity condition. [Results]Space Ginseng Yeast could improve changes of cell morphology and decline of the survival rate caused by microgravity,restore the expression and effective arrangement of cytoskeletal protein Tubulin,extracellular matrix proteins Integrin and Fibronectin,and can inhibit the abnormal expression of MMP-1. The protective effect of Space Ginseng Yeast diluted 20-500 times is better,and the protective effect of Space Ginseng Yeast diluted 100 times is the most obvious. [Conclusions] Space Ginseng Yeast can protect damage of human primary fibroblasts caused by simulated microgravity.[Objectives] To study the protective effect of Space Ginseng Yeast on human primary fibroblasts.[Methods] Multiple indicators were used to simulate the microgravity effect, so as to study the protective effect of Space Ginseng Yeast on human primary fibroblasts under simulated microgravity condition.[Results] Space Ginseng Yeast could improve changes of cell morphology and decline of the survival rate caused by microgravity, restore the expression and effective arrangement of cytoskeletal protein Tubulin, extracellular matrix proteins Integrin and Fibronectin, and can inhibit the abnormal expression of MMP-1. The protective effect of Space Ginseng Yeast diluted 20-500 times is better, and the protective effect of Space Ginseng Yeast diluted 100 times is the most obvious.[Conclusions] Space Ginseng Yeast can protect damage of human primary fibroblasts caused by simulated microgravity.

关 键 词：Anti-aging cosmetics Space Ginseng Yeast Simulated microgravity Human primary fibroblasts Cytoskeletal protein 

分 类 号：S4[农业科学—植物保护]