急性间歇性腹膜透析与持续性血液透析/滤过治疗幼儿毒蕈中毒合并急性肝、肾损伤的效果比较  

Comparison of Acute Intermittent Peritoneal Dialysis and Persistent Hemodialysis/Filtration in Treating Infantile Mushroom Poisoning with Acute Liver and Kidney Injury

作　　者：刘清彪 罗慧嫦 LIU Qing-biao;LUO Hui-chang(Department of pediatrics,Donghua Hospital Affiliated to Zhongshan University,Dongguan 523110,China)

机构地区：[1]中山大学附属东华医院,广东东莞523110

出　　处：《吉林医学》2018年第6期1028-1029,共2页Jilin Medical Journal

摘　　要：目的:评价急性间歇性腹膜透析、持续性血液透析/滤过治疗幼儿毒蕈中毒合并急性肝、肾损伤的临床疗效。方法:回顾分析23例毒蕈中毒合并急性肝、肾损伤患儿的临床资料,并根据治疗方法的不同分为持续组(持续性血液透析/滤过)12例和间歇组(急性间歇性腹膜透析)11例,对比两组患儿的临床疗效。结果:治疗后第3天,两组患儿ALT、AST、Scr、BUN水平均明显下降,持续组优于间歇组,差异有统计学意义(P<0.05)。持续组患儿的透析并发症发生率为8.3%,低于间歇组患儿的36.4%,差异有统计学意义(P<0.05)。持续组死亡率为8.3%,与间歇组死亡率9.1%比较,差异无统计学意义(P>0.05)。结论:持续性血液透析/滤过治疗幼儿毒蕈中毒合并急性肝、肾损伤可获得可靠疗效,与急性间歇性腹膜透析比较并发症更少,安全性更高。Objective To evaluate the clinical efficacy of acute intermittent peritoneal dialysis,continuous hemodialysis/filtration therapy in the treatment of acute liver and kidney injury. Method The clinical data of 23 patients with acute liver and kidney injury were analyzed retrospectively,and were divided into two groups according to the treatment group（ persistent hemodialysis 12 cases） and intermittent group（ acute intermittent peritoneal dialysis 11 cases）,the clinical efficacy of the two groups of children was compared. Results After 3 d,the levels of ALT,AST,Scr and BUN in the two groups were significantly lower than those in the intermittent group（ P〈0.05）. The incidence of dialysis complications was 8. 3% in the continuous group which was lower than 36. 4% in the intermittent group（ P〈0.05）,with a mortality rate of 8. 3% and no significant difference compared with 9. 1% of the children in the intermittent group（ P〈0.05）. Conclusion Continuous hemodialysis/filtration therapy for children with toxic mushroom poisoning with acute liver and kidney injury can be a reliable effect,compared with acute intermittent peritoneal dialysis less complications,higher safety.

关 键 词：急性间歇性腹膜透析 持续性血液透析 幼儿毒蕈中毒 肝损伤 肾损伤 

分 类 号：R725.9[医药卫生—儿科]