黏液水肿性苔藓伴发轻链免疫球蛋白病1例  

A Case of Lichen Myxedematosus with Light Ligand Gammopathy

作　　者：卢晓红 许丛丛 杜文辉[1] 李卉[1] 林达[1] 王培光[1] LU Xiaohong, XU Congcong, DU Wenhui, LI Hui, LIN Da, WANG Peiguang(Department of Dermatology and Venerology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,Chin)

机构地区：[1]安徽医科大学第一附属医院皮肤性病科,安徽合肥230022

出　　处：《中国皮肤性病学杂志》2018年第8期911-913,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者男,52岁,躯干四肢泛发性皮损4个月余。体检:躯干、四肢弥漫密集分布肤色或淡红色扁平丘疹。皮损组织病理示:真皮浅层黏液样变性,真皮胶原纤维增生伴玻璃样变;阿新兰染色阳性。免疫固定电泳:Ig G(+),轻链λ(+)。诊断为黏液水肿性苔藓伴发Ig G-λ轻链免疫球蛋白病。A 52-year-old male presented with widespread rashes in his trunk and limbs for more than 4 months. Physical examination showed diffuse,grouped,skin-colored or reddish flat papules. The lesional histology revealed mucin-like degeneration in the superficial dermis,proliferation and hyaline degeneration of dermal collagen,accompanied by positive alcian blue staining. Immunofixation electrophoresis showed positive immunoglobulin G-λ light chain. Therefore,the patient was diagnosed as lichen myxedematosus associated with IgG-λ light chain gammopathy.

关 键 词：黏液水肿性苔藓 原发性单克隆球蛋白病 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]