南方某省5城市水厂供水中抗生素分布特征与健康风险评估  

Distribution characteristics of selected antibiotics in urban water supply systems in 5 southern cities and their potential health risk analysis

作　　者：曲亚斌[1] 朱炳辉[1] 余胜兵[1] 鲁琳[1] 钟秀华[1] 何昌云[1] 潘尚霞[1] 朱杰民[1] 黄锦叙[1] QU Yabin;ZHU Binghui;YU Shengbing;LU Lin;ZHONG Xiuhua;HE Changyun;PAN Shangxia;ZHU Jiemin;HUANG Jinxu(Guangdong Provincial Center for Disease Control and Prevention,Guangzhou,Guangdong 511430,China)

机构地区：[1]广东省疾病预防控制中心,广东广州511430

出　　处：《职业卫生与应急救援》2018年第3期194-197,共4页Occupational Health and Emergency Rescue

基　　金：广东省医学科研基金(A2015061;A2015227)

摘　　要：[目的]建立饮用水中典型抗生素测定方法,并应用于城市供水中抗生素浓度水平测定与健康风险评估。[方法]选择南方某省5个城市监测水厂作为研究对象,采用固相萃取和超高效液相色谱串联质谱法测定水源水、出厂水、末梢水中48种抗生素分布情况,并利用风险商法评价抗生素通过饮用水途径所致人体健康风险。[结果]水源水检出15种抗生素,水样抗生素总质量浓度为63.31~114.74 ng/L(平均85.27 ng/L)。各水厂供水中检出6种抗生素,其中出厂水抗生素总质量浓度为0.86~7.15 ng/L(平均2.96 ng/L);末梢水中抗生素总质量浓度为0~8.08 ng/L(平均3.28 ng/L)。经过氯化、消毒等水处理工艺,水源水中抗生素去除率为96.52%,其中β-内酰胺类、林可酰胺类和磺胺类完全去除。各水厂供水健康风险商处于较低水平。[结论]监测点水厂供水中仅检出痕量抗生素,不会对人体产生健康危害。[Objective] The typical antibiotics in drinking water were determined to evaluate the distribution characteristics and health risk of antibiotics in urban water supply systems. [Methods] The source water,finished water and tap water were collected from 5 drinking water treatment plants located in south China. The 48 kinds of antibiotics in water were detected by methods of solid-phase extraction（SPE）and ultra-performance liquid chromatography-tandem mass spectrum（UPLC-MS/MS）. Risk Quotients were calculated to assess the health risk of antibiotics pollution in the drinking water. [Results] Totally 15 antibiotics were detected in the source water,and the total concentrations were in range of 63.31-114.74 ng/L（average level was 85.27 ng/L）.Six antibiotics were detected in the water supply systems,and the total concentrations were in range of 0.86-7.15 ng/L（average level was 2.96 ng/L）in the finished water,and the total concentrations were in range of 0-8.08 ng/L（average level was 2.96 ng/L）in the tap water. The water-treatment processes of chlorine disinfection could efficiently remove 96.52% antibiotics,and β-lactams,lincosamides and sulfanilamides could be removed completely. The total health risk caused by antibiotics in drinking water supplied by these plants was very low. [Conclusion] Only a trace number of antibiotics were detected in the water supply plant,which won＇t cause obvious health hazard to the human body.

关 键 词：抗生素 自来水厂 饮用水 健康风险 

分 类 号：X824[环境科学与工程—环境工程]