高效液相色谱—串联质谱法检测鸡蛋中氟虫腈及其代谢物的残留  

Determination of Fipronil and Its Metabolites Residue in Egg by HPLC/MS/MS

作　　者：龚勇[1] 朴秀英[1] 孙丰收 崔凯 廖先骏 李富根[1] Gong Yong;Piao Xiuying;Liao Xianjun;Li Fugen;Cui Kai(Ministry of Agriculture,Beijing 100125,China）（Institute for the Control of Agrochemicals,Sun Fengshou;Center for Pesticide Environmental Toxicology,SDAU,Taian Shandong 271001,China;Institute of quality safety and nutrition of agricultural products,Jiangsu Academy of Agri- cultural Sciences,Nanjing Jiangsu 210014,Chin)

机构地区：[1]农业部农药检定所,北京100125 [2]山东农业大学环境毒理研究中心,山东泰安271001 [3]江苏省农业科学院农产品质量安全与营养研究所,江苏南京210014

出　　处：《农药科学与管理》2018年第3期48-52,共5页Pesticide Science and Administration

摘　　要：建立氟虫腈及其代谢物(氟甲腈、氟虫腈砜、氟虫腈亚砜)在鸡蛋中的残留分析方法。采用乙酸乙酯-环己烷(1:1)提取,GPC净化,通过高效液相色谱-串联质谱进行测定。本方法添加回收率在80.7%～114.3%之间,相对标准偏差在3.4%～15.9%之间,定量限为0.002mg/kg。本方法净化效果好,准确度高,能适用于干扰较强的基质情况。The method for the determination of fipronil and its metabolite（ fipronil desulfinyl,fipronil sulfone and fipronil sulfide） in egg was established. The samples were extracted with ethyl acetate-cyclohexane（1 ： 1）, purified by GPC and finally determined by HPLC/MS/MS. The recoveries of 80. 7% to 114. 3%, the variation coefficients of 3. 4% to 15. 9% and the detection limit of 0. 002 mg/kg were obtained for the method. This method, with good cleaning effect and high accuracy, is applicable of matrix with strong interference.

关 键 词：鸡蛋 氟虫腈 代谢物 残留 GPC 液相色谱-串联质谱 

分 类 号：O657.63[理学—分析化学] TS253.7[理学—化学]