半夏厚朴汤加减联合呼吸功能训练对脑卒中后坠积性肺炎患者神经功能、血清PCT和WBC指标的影响  

Effects of Modified Banxia Houpo Decoction Combined with Respiratory Training on Neurological Function,Serum PCT and WBC Levels in Patients with Post stroke Suspended Pneumonia

作　　者：刘杰[1] 张茜 齐玲[1] LIU Jie;ZHANG Qian;QI Ling(The Sixth Affiliated Hospital to Xinjiang Medical University,,Xinjiang Urumqi China 830002;Xinjiang Uygur Autonomous Region TCM Hospital,Urumqi Xinjiang China 830000)

机构地区：[1]新疆医科大学第六附属医院,新疆乌鲁木齐830002 [2]新疆维吾尔自治区中医医院,新疆乌鲁木齐830000

出　　处：《中医学报》2018年第7期1203-1207,共5页Acta Chinese Medicine

基　　金：新疆维吾尔自治区科技支疆项目计划(指令性)项目(201491175)

摘　　要：目的:观察半夏厚朴汤加减联合呼吸功能训练对脑卒中后坠积性肺炎患者神经功能、血清降钙素原(procalcitonin,PCT)和白细胞计数(white blood cell,WBC)的影响。方法:将63例脑卒中后坠积性肺炎患者按随机数字表法分为对照组31例和观察组32例。两组患者均采用西医基础治疗,对照组在基础治疗基础上加用呼吸功能训练,观察组在对照组治疗基础上加用半夏厚朴汤加减治疗,方药组成:白术30 g,升麻5 g,党参15 g,茯苓15 g,当归10 g,紫苏叶10 g,厚朴10 g,黄芪45 g,陈皮5 g,柴胡5 g,法半夏15 g,生姜15 g,炙甘草10 g,紫苏梗10 g。观察两组患者临床疗效、神经功能缺损评分(neurological deficit score,NDS)及血清PCT、WBC指标变化情况,并观察两组患者不良反应发生情况及对生活质量(quality of life,QOL)评分。结果:观察组有效率为90.63%高于对照组的67.74%,差异有统计学意义(P<0.05);治疗2周后观察组NDS评分、血清PCT和WBC水平均低于对照组,差异均有统计学意义(P<0.05);观察组不良反应发生率为15.63%高于对照组的3.23%,差异无统计学意义(P>0.05);治疗2周后观察组QOL评分高于对照组,差异有统计学意义(P<0.05)。结论:半夏厚朴汤加减联合呼吸功能训练可改善脑卒中后坠积性肺炎患者神经功能、血清PCT和WBC水平,提高患者临床疗效和生活质量,且安全性高。Objective：To observe the effect of Banxia Houpo Decoction combined with respiratory function training on neurological function,serum procalcitonin（ PCT） and white blood cell count（ WBC） levels in patients with post stroke pneumonia. Methods：A total of 63 patients with post stroke pneumonia were divided into observation group and control group,with31 patients in the control group and 32 patients in the observation group,according to the random number table method. The two groups of patients were treated with basic western medicine. The control group was given respiratory function training in addition to the basic treatment.The observation group was treated with modified Banxia Houpo Decoction in addition to that of the control group. The prescription consisted the followings：30 g of Atractylodes Rhizome,5 g of Codonopsis pilosula,and Codonopsis pilosula. 15 g,Poria 15 g,An-gelica 10 g,Perilla leaves 10 g,Magnolia officinalis 10 g,Radix Astragali 45 g,Dried tangerine peel 5 g,Radix Bupleuri 5 g,Radix Pinellia 15 g,Ginger 15 g,Radix Glycyrrhizae 10 g,Basil stems 10 g. The clinical efficacy,neurological deficit score（ NDS）,serum PCT and WBC levels were observed in the two groups,and the occurrence of adverse reactions and quality of life（ QOL）scores were observed in both groups. Results：The effective rate in the observation group was 90. 63%,which was higher than that in the control group（67. 74%）. The difference was statistically significant（ P〈0. 05）. After 2 weeks of treatment,the NDS scores and serum PCT and WBC levels were lower in the observation group than in the control group. There was statistical significance（ P〈0. 05）. The incidence of adverse reactions was 15. 63% in the observation group and 3. 23% in the control group,the difference was not statistically significant（ P〈0. 05）. The QOL score of the observation group was higher than the control group after 2 weeks of treatment. The difference was statistically significant（ P〈0. 05）. Conclusion：Banxia H

关 键 词：脑卒中后坠积性肺炎 半夏厚朴汤 呼吸功能训练 神经功能 血清降钙素原 白细胞计数 中医药疗法 中西医结合 

分 类 号：R259.631[医药卫生—中西医结合]