广州地区婴幼儿急性非细菌感染性腹泻病中医证型特点研究  

Traditional Chinese medical syndromes and treatment strategies of infants with acute non bacterial infectious diarrhea in Guangzhou

作　　者：刘华[1] 许华[1] 欧阳学认[1] 丘小汕[2] 曾永梅 肖达民 温惠红[5] LIU Hual;XU Hua;OUYANG Xueren;QIU Xiaoshan;ZENG Yongmei;XIAO Damin;WEN Huihong(Department of Pediatrics,the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Department of Pediatrics,the First Affiliated Hospital of Zhongshan University,Guangzhou 510080,China;Department of Gastroenterology,Guangzhou Women and Children Medical Center,Guangzhou 510120,China;Department of Pediatrics,Guangzhou Hospital of Traditional Chinese Medicine,Guangzhou 510130,China;Guangzhou University of Chinese Medicine,Guangzhou 510405,China)

机构地区：[1]广州中医药大学第一附属医院儿科,广州510405 [2]中山大学附属第一医院儿科,广州510080 [3]广州市妇女儿童医疗中心消化内科,广州510120 [4]广州市中医院儿科,广州510130 [5]广州中医药大学,广州510405

出　　处：《吉林中医药》2018年第7期808-811,864,共5页Jilin Journal of Chinese Medicine

基　　金：国家"十一五"科技支撑计划中医治疗常见病项目(2007BAI20B024)

摘　　要：目的通过多中心临床研究分析,探讨广州地区婴幼儿急性非细菌感染性腹泻病的中医证型特点、病因病机及治疗对策,为中医药防治婴幼儿急性非细菌感染性腹泻病提供依据。方法选择2009年6月-2011年9月在广州4家医院住院及门诊的急性非细菌感染性腹泻病婴幼儿351例,观察中医证型分布,探讨治疗对策。结果 1)中医证型分布:本研究351例患儿中实证314例(89.46%),虚证37例(10.54%);其中湿热证217例(61.82%),伤食证45例(12.82%),风寒证52例(14.82%),脾虚证37例(10.54%)。2)轮状病毒肠炎阳/阴性的中医证型分布:轮状病毒肠炎患儿140例,其中湿热证101例(72.14%),伤食证14例(10.00%),风寒证19例(13.57%),脾虚证6例(4.29%);轮状病毒阴性患儿211例,其中湿热证115例(54.50%),伤食证27例(12.80%),风寒证39例(18.48%),脾虚证30例(14.22%);轮状病毒阳性组与轮状病毒阴性组的中医证型分布组间差异比较有统计学意义(P<0.05)。3)饮食因素与证型相关性:采用logistic回归分析,体质量、母乳喂养开始时间、母乳喂养持续时间、添加奶粉时间和添加米糊时间与中医证型的相关性不显著(P>0.05)。结论 1)广州地区婴幼儿急性非细菌感染性腹泻中医证型以实证为主,以湿热证更为常见;2)广州地区轮状病毒肠炎婴幼儿中医证型以实证为主,以湿热证更为常见,轮状病毒感染可能影响中医证型分布;3)广州地区婴幼儿体重及相关喂养情况与中医证型分布相关性不显著;4)根据广州地区婴幼儿急性非细菌感染性腹泻的中医证型特点,总结出中药、推拿等临床治疗方案。Objective Through the analysis of multicenter clinical research, to explore the characteristics of traditional Chinese medical syndromes, etiology and pathogenesis and treatment strategies in Guangzhou infants with acute non bacterial diarrhea, and provide the basis for traditional Chinese medicine in treating infants with acute non bacterial infectious diarrhea. Methods To observe the distribution of traditional Chinese medical syndromes and explore the treatment strategies, 351 cases of infants with acute non bacterial infectious diarrhea from Guangzhou four hospitals inpatient and outpatient in June 2009 to September 2011 were recorded. Results 1）In this study, 314 cases of 351 cases were excess syndrome （89.46%）, while deficiency syndrome were 37 cases （10.54%）; 217 cases were damp with heat syndrome （61.82%）, 45 cases were improper diet （12.82%）, 52 cases of wind with cold syndrome （14.82%）, 37 cases were spleen deficiency syndrome （10.54%）. 2）The distribution of traditional Chinese medical syndromes of rotavirus positive/negative： 140 cases rotavirus enteritis, including 101 cases （72.14%） of damp with heat syndrome, 14 cases （10.00%） of improper diet, 19 cases （13.57%） of wind with cold syndrome, 6 cases （4.29%） of spleen deficiency syndrome.In the stool rotavirus for 211 cases were negative, including 115 cases （54.50%） damp with heat syndrome, 27 cases （12.80%） of improper diet, 39 cases （18.48%） of wind with cold syndrome, 30 cases （14.22%） of spleen deficiency syndrome; The differences between traditional Chinese medical syndromes distribution of rotavirus positive group and negative group are statistically significant （P〈 0.05）. 3） Correlation between dietary factors and syndromes： using logistic regression analysis, there was no significant correlation between body weight, breast feeding time, start is not significantly related to breastfeeding duration, add milk time and add the rice paste time and traditional Chinese medicine s

关 键 词：婴幼儿 腹泻 中医证型 广州地区 

分 类 号：R442.2[医药卫生—诊断学]