接受体外受精-胚胎移植治疗的男性抑郁状况及风险因素分析  

Depression and the Risk Factors of Men Undergoing in Vitro Fertilization and Embryo Transfer Treatment

作　　者：李莉[1] 李斐 崔丹 吕晶 张元珍[1] LI Li;LI Fei;ZHANG Yuanzhen(Reproductive medicine center,Zhongnan Hospital of Wuhan University 430071,China)

机构地区：[1]武汉大学中南医院生殖医学中心,湖北武汉430071 [2]华中科技大学同济医学院附属同济医院生殖中心,湖北武汉430030 [3]武汉大学健康学院,湖北武汉430073

出　　处：《中国社会医学杂志》2018年第3期244-247,共4页Chinese Journal of Social Medicine

基　　金：湖北省卫生计生委科研项目(WJ2017H0020)

摘　　要：目的了解接受体外受精-胚胎移植治疗的男性抑郁状况及其风险因素。方法选取726名接受体外受精-胚胎移植治疗的男性,采用一般情况问卷和流调用抑郁自评量表(CES-D)进行问卷调查。采用描述性分析和逻辑回归分析法分析抑郁状况及其相关风险因素。结果接受体外受精-胚胎移植治疗的男性其抑郁检出率为12.97%。不孕原因是抑郁的独立风险因素,与不孕原因为女方因素相比,不孕原因为双方因素和不明原因不孕的男性其抑郁检出率分别是女方因素的2.49(95%CI=1.40~4.45)倍和2.25(95%CI=1.21~4.17)倍。结论接受体外受精-胚胎移植治疗的男性较易出现抑郁症状,尤其是被诊断为不明原因不孕和双方原因不孕的男性,建议对其给予更多的关注,并做好心理疏导。Objective To explore the prevalence of depression in men undergoing in vitro fertilization and embryo transfer（IVF-ET）and the risk factors of depression.Methods 726 men undergoing IVF-ET treatments were involved in the study.Their symptoms of depression were measured by use the Center for Epidemiologic Studies of Depression scale（CES-D）.Logistic regression models was used to identify the risk factors for depression.Results The overall prevalence of depressive symptom was 12.97%for men undergoing IVF-ET treatments.The depression rates of infertility due to both side factors and unexplained factors were 2.49（95% CI = 1.40~4.45）times and 2.25（95% CI = 1.21~4.17）times respectively of infertility due to female side factors.Conclusion The men receiving in vitro fertilization are more likely to experience depressive symptoms,especially men diagnosed with unexplained infertility and infertile causes of both side.Related departments should pay more attention to them and do psychological counseling.

关 键 词：体外受精 抑郁 男性 风险因素 

分 类 号：R719.92[医药卫生—妇产科学] R339.2[医药卫生—临床医学]