妊娠期单核细胞增多性李斯特菌感染及对母儿的影响  

Listeria Monocytogenes infection in pregnancy and its impact on mother and infant

作　　者：肖玲 邹丽颖[2] XIAO Ling1, ZOU Liying2(1.Department of Obstetrics, the First Maternal and Child Health Hospital of Dongehen District, Beijing 100007, China; 2.Department of Obstetrics, Beijing Obstetrics and Gynaecology Hospital, Capital Medical University, Beijing 100026, Chin)

机构地区：[1]北京市东城区第一妇幼保健院产科,北京100007 [2]首都医科大学附属北京妇产医院产科,北京100026

出　　处：《中国医药导报》2018年第15期30-33,共4页China Medical Herald

基　　金：北京市科学技术委员会首都市民健康项目(Z141100002114026);首都医科大学附属北京妇产医院中青年学科骨干培养专项(fcyy201511)

摘　　要：单核细胞增多性李斯特氏菌属于李斯特氏菌属,为人畜共患的致病菌,人类主要是通过食用被污染食品而感染,感染后可导致李斯特菌病。该病原菌可产生一种溶血性外毒素,对人类有很强的致病性,常见于免疫功能低下的者,如妊娠、老年人、免疫缺陷者以及胎儿、新生儿(通过母婴垂直传播或少数者通过阴道分娩时感染)等。人体感染后可引起菌血症、败血症、脑膜炎及流产等症状,因其症状不典型,导致诊断困难。李斯特菌病有较高的死亡率。本文旨在阐述妊娠期单核细胞增多性李斯特菌感染及对母儿的影响,以改善妊娠结局。Listeriosis is an anthropozoonosis caused by Listeria monocytogenes（L. monocytogenes）. It is acquired by humans primarily through consumption of contaminated food. Listeria monocytogenes has strong pathogenicity to human through produced the hemolytictoxin, especially high risk patients such as pregnant women, elderly people, immuno compressed people, unborn babies, andneonates（through vertical transmission from the mother or, more rarely, at birth by ascending colonisation from the vagina）. Infection causes a spectrum of illness, including bacteraemia, sepsis,meningoencephalitis and abortion, but symptoms are nonspecific and diagnosis is difficult. Alsolisteriosishas a highmortality. The aim of this review article is to introduced the relationship between it and pregnacy, so as to improve the pregnancy outcome.

关 键 词：菌血症 单核细胞增多性李斯特氏菌 李斯特菌病 流行病学 妊娠 

分 类 号：R714[医药卫生—妇产科学]