先天性巨结肠术后小肠结肠炎危险因素分析  

Analysis of risk factors of enterocolitis after congenital megacolonectomy

作　　者：莫优炼 胡小华[1] 陈茂芳 段立锋[3] 苏嘉鸿 张平锋[1] 钟陈[1] MO You-lian;HU Xiao-hua;CHEN Mao-fang;DUAN Li-feng;SU Jia-hong;ZHANG Ping-feng;ZHONG Chen(Department of Pediatric Surgery,Affiliated Pok Oi Hospital of Zhongshan City,Southern Medical University,GuangdongProvince,Zhongshan 528408,China;Department of Anesthesiology,Affiliated Pok Oi Hospital of Zhongshan City,Southern Medical University,Guangdong Province,Zhongshan 528408,China;Department of Pathology,Affiliated PokOi Hospital of Zhongshan City,Southern Medical University,Guangdong Province,Zhongshan 528408,China)

机构地区：[1]南方医科大学附属中山市博爱医院小儿外科,广东中山528408 [2]南方医科大学附属中山市博爱医院麻醉科,广东中山528408 [3]南方医科大学附属中山市博爱医院病理科,广东中山528408

出　　处：《中国当代医药》2018年第16期105-107,共3页China Modern Medicine

基　　金：广东省医学科学技术研究基金项目(A2017432)

摘　　要：目的研究先天性巨结肠术后小肠结肠炎的危险因素。方法选取2013年1月~2017年12月在我院行手术治疗的先天性巨结肠患者140例,按照术后是否并发小肠炎分为观察组(46例)和对照组(94例)。观察组为术后并发小肠结肠炎,对照组为未并发小肠结肠炎。探讨相关危险因素。结果术前患有肠炎、上呼吸道或肺部感染、营养不良以及术后吻合口瘘或狭窄、肠梗阻等并发症情况、切除直肠黏膜及内括约肌为先天性巨结肠术后小肠结肠炎患者的单因素;多因素为术前患有肠炎、患有上呼吸道或肺部感染、营养不良。两组的年龄、手术时年龄、病变类型、手术方式、手术切除范围比较,差异无统计学意义(P<0.05)。结论先天性巨结肠术后出现小肠结肠炎的危险因素包括术前患病情况、营养状况、术后并发症发生情况,切除直肠黏膜及内括约肌是避免术后并发小肠结肠炎的有效措施。Objective To study the risk factors of enterocolitis after congenital megacolonectomy.Methods The subjects selected for this study were 140 patients with congenital Hirschsprung′s disease who had undergone surgery in our hospital from January 2013 to December 2017.They were divided the observation group（n=46） and the control group（n=94）by patients complicated or uncomplicated postoperative concurrent enterocolitis.Explore related risk factors.Results Preoperative suffering from enteritis,suffering from upper respiratory tract or lung infection,malnutrition and postoperative anastomotic leakage or stenosis,intestinal obstruction and other complications,resection of rectal mucosa and internal sphincter were congenital megacolon after enterocolitis single factor in patients;multiple factors include preoperative bowel inflammation,upper airway or lung infection,malnutrition.The differences in age,surgical age,lesion type,surgical method,and surgical resection range of the two groups were relatively poor,the difference had no statistical significance（P 〉0.05）.Conclusion The risk factors for enterocolitis after congenital megacolon surgery include preoperative conditions,nutritional status,removal of rectal mucosa and internal sphincter is an effective measure to avoid postoperative colitis.

关 键 词：先天性巨结肠 手术 小肠结肠炎 危险因素 

分 类 号：R726.5[医药卫生—儿科]