白边岛衣多糖抗肿瘤作用的研究  

Studies on the Anti-tumor Effect of Cetraria laevigata Rassad. Polysaccharides

作　　者：王桂芝[1] 李延忠[1] 王本祥[1] 高继山[1] 严仲凯 李晓波 

机构地区：[1]吉林省中医中药研究院,长春130021

出　　处：《中国中药杂志》1991年第4期242-244,共3页China Journal of Chinese Materia Medica

摘　　要：白边岛衣多糖腹腔注射200mg/kg(1/5LD_((?)))能显著抑制小鼠肉瘤180、艾氏腹水癌和宫颈癌-u14等肿瘤的生长,但不能延长白血病L7217小鼠的存活时间,50mg/kg和100mg/kg(1/10和1/20 LD_((?))能增加小鼠网状内皮系统的吞噬功能。The anti-tumor effect of Cetraria laevigata polysaceharides has been investigated in mice using sarcoma 180; Ehrlich ascitie tumor, cervical carcinoma u-14 and leukemia L7217. The results show that Cstraria laevigata polysaccharides may inhibit the growth of sarcoma 180,Ehrlich ascitic tumor and cervical carcinoma u-14 in mice at a dose of 200mg/kg ip (1/5 LD_(50)).However, the survival time of leukemia L7217 wasn't prolonged. The reticuloendothelial system phagocytic function in mice was increased at ip doses of 50mg/kg and 100mg/kg(1/10 and 1/20 LD_(50)).

关 键 词：白边岛衣多糖 抗肿瘤作用 肿瘤 

分 类 号：R282.710.5[医药卫生—中药学]