中西医结合孕前孕后并治不明原因早期复发性流产疗效研究  

Clinical study on the treatment of unexplained early recurrent spontaneous abortion by combination of TCM and western medicine before and after pregnancy

作　　者：陈晶晶 何耀娟 陈爱兰 伍海鹰 陈雯婷 Chen Jingjing;He Yaojuan;Chen Ailan(Adult and Traditional Chinese Medicine,Guangzhou Women and Children Medical CenterGuangzhou 510180)

机构地区：[1]广州市妇女儿童医疗中心成人中医科,广州510180 [2]广州市妇女儿童医疗中心妇婴院区妇科门诊,广州510180

出　　处：《陕西中医》2018年第7期827-829,共3页Shaanxi Journal of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(20164016)

摘　　要：目的:观察中西医结合孕前孕后并治不明原因早期复发性流产临床疗效。方法:回顾分析70例不明原因早期复发性流产患者临床资料,将其随机分为对照组和观察组,每组35例患者。对照组患者采用叶酸片和天然维生素E胶丸治疗,观察组在对照组治疗的基础上服用中药,观察两组患者临床治疗疗效。结果:观察组患者临床治疗总有效率为74.28%,明显高于对照组患者临床治疗总有效率42.85%,差异有统计学意义(P<0.05);观察组患者成功妊娠率、早期自然流产率、继发不孕率与对照组对比,差异有统计学意义(P<0.05);观察组早孕期的孕酮、β-HCG值均明显高于对照组,差异有统计学意义(P<0.05);观察组早孕期先兆流产症候评分明显低于对照组,差异有统计学意义(P<0.05);在观察和治疗期间,两组患者不良反应发生率对比差异无统计学意义(P>0.05)。结论:中西医结合孕前孕后并治不明原因早期复发性流产疗效确切,值得临床应用。Objective：To observe the clinical efficacy of integrative traditional Chinese medicine（TCM）and intestine pregnancy in treating early recurrent abortion of unknown causes.Methods：The clinical data of 70 patients with early unexplained recurrent spontaneous abortion were retrospectively analyzed.They were randomly divided into control group and observation group with 35 patients in each group.Patients in the control group were treated with folic acid tablets and natural vitamin E capsules.The observation group took traditional Chinese medicine on the basis of the treatment of the control group,and the clinical efficacy of the two groups was observed.Results：The total effective rate of clinical treatment in observation group was 74.28%,which was significantly higher than that in control group（42.85%）,the difference was statistically significant（P〈0.05）;The observation group of patients with successful pregnancy rate,early abortion rate,secondary infertility rate compared with the control group,the differences were statistically significant（P〈0.05）;The progesterone andβ-HCG values of observation group in early pregnancy were significantly higher than those in control group,the differences were statistically significant（P〈0.05）.The scores of first trimester threatened abortion syndrome were significantly lower than the control group,the difference was statistically significant（P〈0.05）;during the period of observation and treatment,two groups of patients with adverse reaction rate comparison,the difference was not statistically significant（P〉0.05）.Conclusion：Integrative medicine preconception pregnancy and cure unexplained early recurrent abortion curative effect is worthy of clinical promotion and application.

关 键 词：流产/中西医结合疗法 补肾剂/治疗应用 温补脾肾 

分 类 号：R714.21[医药卫生—妇产科学]