通脉逐瘀方联合阿司匹林治疗肺心病急性加重期合并全身炎症反应综合征疗效及对患者血浆D-二聚体、IL-6、BNP的影响  

Effect of Tongmai Zhuyu decoction combined with aspirin on acute exacerbation of pulmonary heart disease combined with systemic inflammatory response syndrome and its effects on plasma D-dimer,IL-6 and BNP

作　　者：庞海江 Pang Haijiang(Department of Emergency,Zhengzhou City Traditional Chinese Medicine Hospital（Zhengzhou 450000)

机构地区：[1]郑州市中医院急诊科,郑州450000

出　　处：《陕西中医》2018年第7期873-875,共3页Shaanxi Journal of Traditional Chinese Medicine

基　　金：河南省重点科技攻关计划项目(082102310078)

摘　　要：目的:探讨通脉逐瘀方联合阿司匹林治疗肺心病急性加重期合并全身炎症反应综合征的疗效及对患者血浆D-二聚体、IL-6、BNP的影响。方法:随机将68例肺心病急性加重期合并全身炎症反应综合征患者分为两组,每组34例。以接受常规基础治疗者为对照组,以接受常规基础治疗联合通脉逐瘀方、阿司匹林治疗者为治疗组。结果:两周治疗后,治疗组PaO2显著高于对照组(P<0.05),PaO_2、血浆D-二聚体、IL-6、BNP水平均显著低于对照组(P<0.05)。同时,治疗组临床总有效率(91.18%)明显高于对照组(79.41%)(P<0.05)。结论:肺心病急性加重期合并全身炎症反应综合征治疗中,通脉逐瘀方联合阿司匹林可提升患者的临床治疗效果。Objective：To explore the effect of Tongmai Zhuyu decoction combined with aspirin in the treatment of acute exacerbation of pulmonary heart disease combined with systemic inflammatory response syndrome,and to explore the effect on the plasma levels of D-dimer,IL-6 and BNP.Methods：68 patients with acute exacerbation of pulmonary heart disease combined with systemic inflammatory response syndrome were randomly divided into two groups,34 cases in each group.To accept conventional basic treatment for the control group,to accept conventional basic treatment combined with Tongmai Zhuyu decoction and aspirin for the treatment group.Results：After 2 weeks treatment,the level of PaO2 in the treatment group was significantly higher than that in the control group（P〈0.05）,and the levels of PaO2,D-dimer,IL-6 and BNP were significantly lower than those in the control group（P〈0.05）.Meanwhile,the total effective rate in the treatment group（91.18%）was significantly higher than that in the control group（79.41%）（P〈0.05）.Conclusion：Tongmai Zhuyu decoction combined with aspirin can improve the clinical effect of patients with acute exacerbation of pulmonary heart disease combined with systemic inflammatory response syndrome.

关 键 词：肺心病/中西医结合疗法 @通脉逐瘀方 阿司匹林 

分 类 号：R541.5[医药卫生—心血管疾病]