羟苯基丙酰胺苯甲酸的合成  

Synthesis of Hydroxyphenyl Propamidobenzoic Acid

作　　者：李振建 张帅波 刘潮 冯柏成[1] 金岩[1] 任相忠 LI Zhen-jian;ZHANGShuai-bo;LIU Chao;FENG Bai-cheng;JINYan;RENXiang-zhong(College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China;Jinan Research Institute of Chemical Industry,Jinan 250101,China)

机构地区：[1]青岛科技大学化工学院,山东青岛266042 [2]济南市化工研究所,山东济南250101

出　　处：《合成化学》2018年第6期437-439,共3页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金区域基金资助项目(31760521)

摘　　要：以苯酚为起始原料,经碳烷基化反应、水解反应、酰氯反应、酰胺反应和水解酸化等5步反应合成了羟苯基丙酰胺苯甲酸,纯度大于99.0%,其结构经1H NMR和IR确证。Hydroxyphenyl propamidobenzoic acid,with purity of above 99. 0%,was synthesized by the reaction of alkylation,hydrolyzation,chloridization,amidation and hydrolysis-acidification,using phenol as the starting material. The structure was confirmed by1 H NMR and IR.

关 键 词：苯酚 羟苯基丙酰胺苯甲酸 合成 条件优化 

分 类 号：O625.5[理学—有机化学]