二维和三维数字化塑形钛网修补颅骨后并发症的异同  

Similarities and differences on complications after cranioplasty with two-dimensional and three-dimensional digital shaping titanium meshes

作　　者：胡均贤[1] 袁玉明[1] 赵德英 徐春林[1] 吴雅兰[1] Hu Jun-xian;Yuan Yu-ming;Zhao De-ying;Xu Chun-lin;Wu Ya-lan(Huanggang Center Hospital,Huanggang 438000,Hubei Province,China)

机构地区：[1]黄冈市中心医院,湖北省黄冈市438000

出　　处：《中国组织工程研究》2018年第18期2826-2830,共5页Chinese Journal of Tissue Engineering Research

基　　金：湖北省卫生和计划生育委员会科研项目(WJ2017F088)~~

摘　　要：背景:颅骨缺损患者行颅骨修补后可发生与材料相关及不相关的并发症。目的:探讨二维和三维数字化塑形钛网修补颅骨后的并发症异同。方法:回顾性分析221例颅骨修补患者的临床资料,其中61例采用二维数字化塑形钛网修补材料,160例采用三维数字化塑形钛网修补材料,总结两组修补后发生与修补材料相关并发症(包括钛网钛钉外露与钛钉松动翘起)及不相关并发症(包括顽固性皮下积液、癫痫、头皮坏死、头皮感染、颅内感染和颅内血肿)的情况。结果与结论:二维数字化塑形钛网修补组发生并发症14例,包括顽固性皮下积液2例、癫痫7例、钛网钛钉外露2例、钛网钛钉松动翘起2例、皮感染1例,最后统计发生与修补材料相关并发症4例,与修补材料不相关并发症10例;三维数字化塑形钛网修补组发生并发症17例,包括顽固性皮下积液5例、癫痫9例、头皮坏死1例、颅内感染1例、颅内血肿1例,最后统计发生与修补材料相关并发症0例,与修补材料不相关并发症17例;两组发生与材料相关并发症例数差异显著(χ~2=5.577,P=0.018);结果表明,使用三维数字化塑形钛网修补颅骨后的与材料相关并发症发生情况低于二维数字化塑形钛网。BACKGROUND： Patients with cranial defects undergoing cranioplasty can develop complications related or unrelated to repair materials. OBJECTIVE： To explore the differences and similarities between the two-dimensional and three-dimensional digital shaping titanium meshes for cranioplasty. METHODS： The clinical data of 221 patients with skull repair were retrospectively analyzed. Two-dimensional digital shaping titanium mesh was used in 61 cases, and three-dimensional digital shaping titanium mesh used in 160 cases. Postoperative complications related （including exposure of titanium mesh and nail and loosening of titanium nail） or unrelated （including refractory subcutaneous effusion, epilepsy, scalp necrosis, scalp infection, intracranial infection and intracranial hematoma） to repair materials were summarized. RESULTS AND CONCLUSION： There were 14 cases of complications （4 related and 10 unrelated） in the two-dimensional digital shaping titanium mesh group, including 2 cases of intractable subcutaneous effusion, 7 cases of epilepsy, 2 cases of titanium mesh and nail exposure, 2 cases of titanium mesh and titanium nail loosening and 1 case of scalp infection. There were 17 cases of complications （0 related and 17 unrelated） in the three-dimensional digital shaping titanium mesh group, including 5 cases of refractory subcutaneous effusion, 9 cases of epilepsy, 1 case of scalp necrosis, 1 case of intracranial infection and 1 case of intracranial hematoma. Significant differences in the complications related to repair materials were found between the two groups （χ2=5.577, P=0.018）. Overall findings suggest that the craniotomy with three-dimensional digital shaping titanium mesh can cause fewer material-related complications than that with two-dimensional digital shaping titanium mesh.

关 键 词：三维数字化塑形钛网 二维数字化塑形钛网 颅骨修补 数字化塑形技术 钛合金 钛网 并发症 生物材料 

分 类 号：R318[医药卫生—生物医学工程]