卡前列素氨丁三醇联合缩宫素治疗剖宫产产后出血效果的影响因素  

Influencing factors of the efficacy of the combination of Carboprost Tromethamine and Oxytocin in the treatment of postpartum hemorrhage after cesarean section

作　　者：赵雅玲[1] ZHAO Ya-ling(Department of Obstetrics and Gynecology,Chang＇an Hospital in Dongguan City,Guangdong Province,Dongguan 523800,China)

机构地区：[1]广东省东莞市长安医院妇产科,广东东莞523800

出　　处：《中国当代医药》2018年第17期146-148,155,共4页China Modern Medicine

摘　　要：目的探讨卡前列素氨丁三醇联合缩宫素治疗剖宫产产后出血效果的影响因素。方法回顾性分析2015年9月~2017年9月广东省东莞市长安医院收治的采用卡前列素氨丁三醇和缩宫素联合治疗的140例剖宫产产后出血产妇的临床资料,根据临床治疗效果分为有效组(n=120)和无效组(n=20)。对可能影响患者治疗效果的因素分别进行单因素描述性分析和多因素Logistic回归分析。结果无效组产妇的年龄≥35岁、瘢痕子宫妊娠、双胎或多胎、胎儿窘迫、前置胎盘、孕次>3次、小骨盆构成比均远高于有效组,差异有统计学意义(χ2=23.770、61.920、21.672、9.047、4.543、7.426、15.084,P<0.05)。经Logistic回归分析可知,年龄≥35岁、瘢痕子宫妊娠、双胎或多胎、胎儿窘迫、前置胎盘、孕次>3次、小骨盆均为影响患者疗效的独立危险因素(OR=12.475、19.643、11.120、5.407、4.144、4.071、6.745,P<0.05)。结论年龄越大,卡前列素氨丁三醇联合缩宫素治疗剖宫产产后出血的效果越不理想,此外还有多种危险因素较为常见,应当针对上述危险因素分析结果制定针对性的改善疗效的策略,以期促进剖宫产产后出血患者的快速康复,保证产后恢复。Objective To explore the influencing factors of the efficacy of the combination of Carboprost Tromethamine and Oxytocin in the treatment of postpartum hemorrhage after cesarean section.Methods A retrospective analysis of 140 cases of cesarean section postpartum hemorrhage treated with Carboprost Tromethamine combined with Oxytocin in Chang′an Hospital in Dongguan City of Guangdong Province from September 2015 to September 2017 were carried out.According to the effect of clinical treatment,the patients were divided into effective group（n=120） and ineffective group（n=20）.Single factor descriptive analysis and multiple factor Logistic regression analysis of factors that may affect the efficacy of such patients treated with Carboprost Tromethamine and Oxytocin were determined.Results The rates of age ≥35 years old,uterine scar pregnancy,multi fetus,fetal distress,double or multiple births,placenta previa,gestational times 3 and small pelvis in the ineffective group were much higher than those in the effective group,the differences were statistically significant（χ2=23.770,61.920,21.672,9.047,4.543,7.426,15.084,P〈0.05）.The age ≥35 years old,uterine scar pregnancy,multi fetus,fetal distress,double or multiple births,placenta previa,gestational times 3 and small pelvis were independent risk factors affecting the efficacy by Logistic regression analysis（OR=12.475,19.643,11.120,5.407, 4.144,4.071,6.745,P〈0.05）.Conclusion The greater the age,the less effective the treatment of postpartum hemorrhage treated with Carboprost Tromethamine combined with Oxytocin,in addition,there are a variety of risk factors that are more common.In order to promote the rapid recovery of postpartum hemorrhage in caesarean section and guarantee the recovery of postpartum hemorrhage,the strategies of improving the curative effect should be formulated according to the analysis of the above risk factors.

关 键 词：年龄因素 卡前列素氨丁三醇 缩宫素 剖宫产 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]