硝普钠对PCI相关的围手术期心肌梗死的影响  

Effects of Sodium Nitroprusside on PCI-related Perioperative Myocardial Infarction

作　　者：阚亚柏 王徐乐[1] 邱春光[1] 韩战营[1] KAN Ya-bai;WANG Xu-le;QIU Chun-guang(Cardiovascular Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院心内科,河南郑州450052

出　　处：《医学与哲学（B）》2018年第6期32-34,47,共4页Medicine & Philosophy(B)

基　　金：2016年国家自然科学基金项目(8160027)

摘　　要：评估在择期PCI手术中冠状动脉内注射硝普钠预防PCI相关的围手术期心肌梗死的安全性、有效性。选取郑州大学第一附属医院心血管内科2017年2月~2017年8月有稳定或不稳定型心绞痛缺血证据,择期行PCI治疗的患者100例。将所选患者随机分为两组:治疗组(n=50)和对照组(n=50),收集入选患者相关临床资料,采用SPSS 21.0软件进行统计分析。与对照组相比,治疗组PCI相关的围手术期心肌梗死发生率明显降低(P<0.05)。因此,PCI术中经冠状动脉内注射硝普钠能够有效降低围手术期心肌梗死的发生率。To evaluate the safety and efficacy of intracoronary sodium nitroprusside for PCI-related perioperative myocardial infarction during elective PCI.From February 2017 to August 2017,a total of 100 patients with elective PCI were selected.The selected patients were randomly divided into two groups：treatment group（n=50）and control group（n=50）.Clinical data of the selected patients was collected,and statistical analysis was performed using SPSS 21.0 software.Compared with the control group,the incidence of PCI-related perioperative myocardial infarction was significantly lower in the treatment group（P〈0.05）.Therefore,the intracoronary injection of sodium nitroprusside during PCI can effectively reduce the incidence of perioperative myocardial infarction.

关 键 词：冠心病 经皮冠状动脉介入治疗 围术期心肌梗死 硝普钠 

分 类 号：R541.4[医药卫生—心血管疾病]