观察乌龙丹联合柳氮磺吡啶治疗强直性脊柱炎的疗效与安全性  

Observation on efficacy and safety of Wulongdan combined with sulfasalazine in the treatment of ankylosing spondylitis

在线阅读下载全文

作  者:张圳锋 林桂娥 徐培青 ZHANG Zhen-feng;LIN Gui-e;XU Pei-qing(Shenzhen Dapeng New District Nan' ao People' s Hospital,Shenzhen 518121,China)

机构地区:[1]深圳市大鹏新区南澳人民医院,518121

出  处:《中国现代药物应用》2018年第12期82-83,共2页Chinese Journal of Modern Drug Application

摘  要:目的探析乌龙丹联合柳氮磺吡啶治疗强直性脊柱炎的疗效与安全性。方法 40例强直性脊柱炎患者为研究对象,随机分为对照组和观察组,每组20例。对照组给予柳氮磺吡啶治疗,观察组采用乌龙丹联合柳氮磺吡啶治疗,对比分析两组患者治疗效果、脊柱活动度、腰椎骨密度及不良反应发生情况。结果观察组的临床疗效为95.00%,明显高于对照组的70.00%,差异有统计学意义(P<0.05)。治疗后,两组患者脊柱活动度、腰椎骨密度均优于治疗前,观察组明显优于对照组,差异有统计学意义(P<0.05)。观察组的不良反应发生率为5.00%低于对照组的30.0%,差异有统计学意义(P<0.05)。结论在强直性脊柱炎的临床治疗上,采用乌龙丹联合柳氮磺吡啶的治疗方法临床疗效更为显著,且治疗安全性高,故可推广和应用。Objective To investigate and analyze the efficacy and safety of Wulongdan combined with sulfasalazine in the treatment of ankylosing spondylitis. Methods A total of 40 ankylosing spondylitis patients as study subjects were randomly divided into control group and observation group, with 20 cases in each group. The control group was treated with sulfasalazine, and the observation group was treated with Wulongdan combined with sulfasalazine. Comparison and analysis were made on treatment effect, spinal activity, lumbar spine bone density and occurrence of adverse reactions between the two groups. Results The observation group had obviously higher clinical efficacy as 95.00% than 70.00% in the control group, and the difference was statistically significant(P〈0.05). After treatment, both groups had better spinal activity and lumbar spine bone density than before treatment, and the observation group was obviously better than the control group. Their difference was statistically significant(P〈0.05). The observation group had lower incidence of adverse reactions as 5.00% than 30.0% in the control group, and the difference was statistically significant(P〈0.05). Conclusion Application of Wulongdan and sulfasalazine shows remarkable clinical efficacy in clinical treatment of ankylosing spondylitis with high treatment safety, and it can be promoted and applied.

关 键 词:乌龙丹 柳氮磺吡啶 强直性脊柱炎 疗效 安全性 

分 类 号:R593.23[医药卫生—内科学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象