替罗非班致重度血小板减少1例  被引量:2

One case of serious thrombocytopenia induced by tirofiban

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作  者:李艳娇[1] 董雷[1] 宋燕青[1] LI Yan-jiao;DONG Lei;SONG Yan-qing(Pharmaceutical Department,Jilin University,Changchun 130021,China)

机构地区:[1]吉林大学第一医院药学部,吉林长春130021

出  处:《中国药物应用与监测》2018年第3期185-187,共3页Chinese Journal of Drug Application and Monitoring

摘  要:1例62岁男性患者,因急性下壁心肌梗死给予阿司匹林、氯吡格雷抗血小板聚集,以及依诺肝素抗凝治疗,入院第3天查血常规示血小板237×10~9·L^(-1),并于当天行冠状动脉支架植入术,术后给予替罗非班强化抗血小板聚集治疗。入院第4天查血常规示血小板37×10~9·L^(-1),立即停用替罗非班及伊诺肝素,其他抗栓药物继续使用,入院第7天复查血常规示血小板恢复正常,之后未再出现血小板减少,患者于病情稳定后出院。A 62-year-old male patient presented with acute inferior wall myocardial infarction.The patient was treated with aspirin,clopidogrel and enoxaparin after admission.On the 3^rd day,he underwent primary percutaneous coronary intervention(PCI)with a normal blood platelet count(237×10^9·L^-1).Tirofiban was given to him after PCI.On the 4^th day,the blood platelet count dropped to 37×10^9·L^-1.So tirofiban and enoxaparin was immediately withdrawn.On the 7^th day,blood routine test showed platelet count increased to normal range.Thereafter the blood platelet count was stable and the patient was discharged with stable station.

关 键 词:替罗非班 血小板减少 药品不良反应 

分 类 号:R969.3[医药卫生—药理学]

 

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